5-(4-氟苯基)-呋喃-2-甲醛合成路线 （共 7 条）
反应条件
potassium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; tetrakis(triphenylphosphine) palladium(0) in ethanol; water; toluene Suzuki coupling; 5 h; Heating;
参考文献
Mitsch, Andreas; Wissner, Pia; Silber, Katrin; Haebel, Peter; Sattler, Isabel; Klebe, Gerhard; Schlitzer, Martin
Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 17 p. 4585 - 4600
反应条件
bis-triphenylphosphine-palladium(II) chloride; sodium carbonate in ethylene glycol dimethyl ether; ethanol; water T=50°C; Suzuki reaction; 3 h;
参考文献
Hosoya, Takamitsu; Aoyama, Hiroshi; Ikemoto, Takaaki; Kihara, Yasutaka; Hiramatsu, Toshiyuki; Endo, Makoto; Suzuki, Masaaki
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 5 p. 663 - 673
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(I) bromide in ethylene glycol dimethyl ether T=50°C; Stille reaction; 12 h;
参考文献
Hosoya, Takamitsu; Aoyama, Hiroshi; Ikemoto, Takaaki; Kihara, Yasutaka; Hiramatsu, Toshiyuki; Endo, Makoto; Suzuki, Masaaki
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 5 p. 663 - 673
反应条件
palladium diacetate; caesium carbonate; triphenylphosphine in 1-methyl-pyrrolidin-2-one T=90°C; 1 h;
参考文献
Rao, Maddali L. N.; Awasthi, Dheeraj K.; Talode, Jalindar B.
Synlett, 2012 , vol. 23, # 13 p. 1907 - 1912
反应条件
potassium acetate; palladium diacetate in N,N-dimethyl acetamide T=150°C; 20 h; Inert atmosphere;
参考文献
Dong, Jia Jia; Roger, Julien; Pogan, Franc; Doucet, Henri
Green Chemistry, 2009 , vol. 11, # 11 p. 1832 - 1846
反应条件
hydrogenchloride; sodium nitrite 1.) water, 0.5 h, 0 to 5 deg C; 2.) acetone, 0 deg C; Multistep reaction;
参考文献
Ying; Bao-Ju; Ling; Miao, Hong-Jian; Yan-Xia; Yang, Xin-Ling
Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 5 p. 3037 - 3042
反应条件
sodium hydride 1.) THF, 2.) DMF, 0.5h; Yield given. Multistep reaction;
参考文献
Brooks; Stewart; Basha; Bhatia; Ratajczyk; Martin; Craig; Kolasa; Bouska; Lanni; Harris; Malo; Carter; Bell
Journal of Medicinal Chemistry, 1995 , vol. 38, # 24 p. 4768 - 4775
