1,4,5,6-四氢吡啶-3-羧酸乙酯合成路线 （共 8 条）
反应条件
hydrogen; palladium on activated charcoal in ethanol T=20°C; P=5171.48 Torr; 36 h;
参考文献
Lei, Aiwen; Chen, Mao; He, Minsheng; Zhang, Xumu
European Journal of Organic Chemistry, 2006 , # 19 p. 4343 - 4347
反应条件
N-phenyl carbamic acid isopropyl ester; hydrogen; [Rh(μ-Cl)(2,5-norbornadiene)]2 in tetrahydrofuran T=60°C; P=75006 Torr; 18 h; Product distribution; Further Variations:ReagentsSolvents;
参考文献
Studer, Martin; Wedemeyer-Exl, Christina; Spindler, Felix; Blaser, Hans-Ulrich
Monatshefte fur Chemie, 2000 , vol. 131, # 12 p. 1335 - 1343
反应条件
1: tetrahydrofuran 2: 25 percent / NaBH4 / methanol / 2 h View Scheme
参考文献
Sundberg, Richard J.; Walters, Claudia Powers; Bloom, Jonathan D.
Journal of Organic Chemistry, 1981 , vol. 46, # 18 p. 3730 - 3732
反应条件
1: 36 percent / P2S5 / toluene / Ambient temperature 2: tetrahydrofuran 3: 25 percent / NaBH4 / methanol / 2 h View Scheme
参考文献
Sundberg, Richard J.; Walters, Claudia Powers; Bloom, Jonathan D.
Journal of Organic Chemistry, 1981 , vol. 46, # 18 p. 3730 - 3732
反应条件
1: BuLi / -78 °C 2: H2 / [Rh((S,S,R,R)-Tangphos)NBD][SbF6] / CH2Cl2 / 72 h / 80 °C / 77572.2 Torr View Scheme
参考文献
Lei, Aiwen; Chen, Mao; He, Minsheng; Zhang, Xumu
European Journal of Organic Chemistry, 2006 , # 19 p. 4343 - 4347
反应条件
1.1: BuLi / hexane / -78 °C 1.2: hexane 2.1: H2 / [Rh((S,S,R,R)-Tangphos)NBD][SbF6] / CH2Cl2 / 72 h / 80 °C / 77572.2 Torr View Scheme
参考文献
Lei, Aiwen; Chen, Mao; He, Minsheng; Zhang, Xumu
European Journal of Organic Chemistry, 2006 , # 19 p. 4343 - 4347
反应条件
platinum on carbon; hydrogen in acetic acid
T=100°C; P=75007.5 Torr; Continuous flow;
参考文献
Irfan, Muhammed; Petricci, Elena; Glasnov, Toma N.; Taddei, Maurizio; Kappe, C. Oliver
European Journal of Organic Chemistry, 2009 , # 9 p. 1327 - 1334
反应条件
1: BuLi / -78 °C
2: H2 / [Rh((S,S,R,R)-Tangphos)NBD][SbF6] / CH2Cl2 / 72 h / 80 °C / 77572.2 Torr
View Scheme
参考文献
Lei, Aiwen; Chen, Mao; He, Minsheng; Zhang, Xumu
European Journal of Organic Chemistry, 2006 , # 19 p. 4343 - 4347
