2-[氨基(苯基)亚甲基]丙二腈合成路线 （共 14 条）
反应条件
ammonia in ethanol 0.25 h; Ambient temperature;
参考文献
Kappe, C. Oliver; Flammang, Robert; Wentrup, Curt
Heterocycles, 1994 , vol. 37, # 3 p. 1615 - 1622
参考文献
Journal of the American Chemical Society, , vol. 80, p. 2815,2820
反应条件
1: 65 percent / Ac2O / 120 h / 65 °C 2: 97 percent / NH3 / ethanol / 0.25 h / Ambient temperature View Scheme
参考文献
Heterocycles, , vol. 37, # 3 p. 1615 - 1622
反应条件
1: HCl (gas) / toluene / 20 h / Ambient temperature 2: Et3N / methanol / 2 h / Heating View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 33, # 6 p. 1903 - 1907
反应条件
triethylamine in methanol 2 h; Heating;
参考文献
Journal of Heterocyclic Chemistry, , vol. 33, # 6 p. 1903 - 1907
反应条件
1: sodium hydride / tetrahydrofuran / 2 h / 0 - 5 °C 2: trichlorophosphate / Reflux 3: ammonium hydroxide / 2 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 9 p. 3223 - 3228
反应条件
ammonium hydroxide T=20°C; 2 h;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 9 p. 3223 - 3228
反应条件
1: NaHCO3; aqueous dioxane 2: aqueous NH3 View Scheme
参考文献
Chemische Berichte, , vol. 91, p. 1830,1832
反应条件
1: trichlorophosphate / Reflux 2: ammonium hydroxide / 2 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 9 p. 3223 - 3228
反应条件
sodium methylate 1.) MeOH, 72 h, 2.) 1.5 h; Yield given. Multistep reaction;
参考文献
Journal of Chemical Research, Miniprint, , # 3 p. 958 - 975
