3-(乙氧基羰基)-1,4-二甲基-1H-吡咯-2-乙酸乙酯合成路线 （共 16 条）
反应条件
hydrogenchloride; methylamine in dichloromethane
参考文献
Ethyl Corporation
Patent: US4565878 A1, 1986 ;
反应条件
sulfuric acid in ethanol; water T=75 - 80°C; 1.25 h;
参考文献
Stahly, G. P.; Marlett, E. M.; Nelson, G. E.
Journal of Organic Chemistry, 1983 , vol. 48, # 23 p. 4423 - 4426
反应条件
sulfuric acid in ethanol; water T=75 - 80°C; 1.25 h;
参考文献
Stahly, G. P.; Marlett, E. M.; Nelson, G. E.
Journal of Organic Chemistry, 1983 , vol. 48, # 23 p. 4423 - 4426
反应条件
in water T=15 - 40°C; 1 h;
参考文献
Manoni, Francesco; Connon, Stephen J.
Angewandte Chemie - International Edition, 2014 , vol. 53, # 10 p. 2628 - 2632
Angew. Chem., 2014 , vol. 126, # 10 p. 2666 - 2670,5
参考文献
Cell Pathways, Inc.; University of Arizona
Patent: US5721347 A1, 1998 ;
反应条件
sodium hydroxide in water T=100°C; 3 h;
参考文献
Manoni, Francesco; Connon, Stephen J.
Angewandte Chemie - International Edition, 2014 , vol. 53, # 10 p. 2628 - 2632
Angew. Chem., 2014 , vol. 126, # 10 p. 2666 - 2670,5
参考文献
Cell Pathways Inc
Patent: US5939417 A1, 1999 ;
反应条件
phosphoric acid T=80°C; 1 h;
参考文献
Zinic, M.; Kuftinec, J.; Hofman, H.; Kajfez, F.; Meic, Z.
Journal of Organic Chemistry, 1985 , vol. 50, # 5 p. 697 - 700
反应条件
sulfuric acid in ethanol T=60°C; var. reaction times; Product distribution;
参考文献
Stahly, G. P.; Marlett, E. M.; Nelson, G. E.
Journal of Organic Chemistry, 1983 , vol. 48, # 23 p. 4423 - 4426
反应条件
sulfuric acid in ethanol T=60°C; var. reaction times; Product distribution;
参考文献
Stahly, G. P.; Marlett, E. M.; Nelson, G. E.
Journal of Organic Chemistry, 1983 , vol. 48, # 23 p. 4423 - 4426
