4-羟基-3,5-二碘苯甲酸甲酯合成路线 （共 18 条）
反应条件
SPC; potassium iodide in water; acetic acid T=50°C; Inert atmosphere;
参考文献
Takagi, Akira; Ikawa, Takashi; Kurita, Yurio; Saito, Kozumo; Azechi, Kenji; Egi, Masahiro; Itoh, Yuji; Tokiwa, Hiroaki; Kita, Yasuyuki; Akai, Shuji
Tetrahedron, 2013 , vol. 69, # 21 p. 4338 - 4352
反应条件
sulfuric acid T=65°C; 23 h;
参考文献
Chen, Li-Jun; Li, Quan-Jie; He, Jiuming; Tan, Hongwei; Abliz, Zeper; Yang, Hai-Bo
Journal of Organic Chemistry, 2012 , vol. 77, # 2 p. 1148 - 1153
反应条件
TiCl4 in methanol; diethyl ether
参考文献
Butera, John A.; Caufield, Craig E.; Graceffa, Russell F.; Greenfield, Alexander; Gundersen, Eric G.; Havran, Lisa Marie; Katz, Alan H.; Lennox, Joseph R.; Mayer, Scott C.; McDevitt, Robert E.
Patent: US6214877 B1, 2001 ;
反应条件
chloramine-T; sodium iodide in acetonitrile T=20°C; 1.5 h;
参考文献
Lang, Martin; Steglich, Wolfgang
Synthesis, 2005 , # 6 art. no. Z01205SS, p. 1019 - 1027
反应条件
1: methyl 4-hydroxy-benzoate With chloramine-T; sodium iodide in acetonitrile T=20°C; 1.5 h; 2: chloromethyl methyl ether With N,N-diethyl-N-isopropylamine in dichloromethane; ethyl acetate T=20°C; 5 h; Title compound not separated from byproducts;
参考文献
Lang, Martin; Steglich, Wolfgang
Synthesis, 2005 , # 6 art. no. Z01205SS, p. 1019 - 1027
反应条件
2: potassium permanganate; magnesium sulfate 3: concentrated hydrochloric acid 4: Diazotization 5: concentrated sulfuric acid View Scheme
参考文献
Wheeler; Liddle
American Chemical Journal, 1909 , vol. 42, p. 457
反应条件
1: potassium permanganate; magnesium sulfate 2: concentrated hydrochloric acid 3: Diazotization 4: concentrated sulfuric acid View Scheme
参考文献
Wheeler; Liddle
American Chemical Journal, 1909 , vol. 42, p. 457
反应条件
1: concentrated hydrochloric acid 2: Diazotization 3: concentrated sulfuric acid View Scheme
参考文献
Wheeler; Liddle
American Chemical Journal, 1909 , vol. 42, p. 457
反应条件
1: Diazotization 2: concentrated sulfuric acid View Scheme
参考文献
Wheeler; Liddle
American Chemical Journal, 1909 , vol. 42, p. 457
反应条件
1: diluted hydrochloric acid; monochloroiodo 2: Diazotization 3: concentrated sulfuric acid View Scheme
参考文献
Wheeler; Liddle
American Chemical Journal, 1909 , vol. 42, p. 457
