反应条件
1: 2-methyl-4,5,6,7-tetrahydro-3H-azepine With lithium diisopropyl amide in tetrahydrofuran; hexane T=-30°C; Metallation; 1 h; 2: methyl iodide in tetrahydrofuran; hexane T=-78 - 20°C; Substitution; 3 h;
参考文献
Brimble, Margaret A.; Gorsuch, Stephen
Australian Journal of Chemistry, 1999 , vol. 52, # 10 p. 965 - 969