2-乙基-4,5,6,7-四氢-3H-氮杂卓合成路线 (共 3 条)
反应条件
boric acid T=180°C; 0.75 h;
参考文献
Bacos, Daniel; Celerier, Jean-Pierre; Lhommet, Gerard
Tetrahedron Letters, 1987 , vol. 28, # 21 p. 2353 - 2354
反应条件
1: 2-methyl-4,5,6,7-tetrahydro-3H-azepine With lithium diisopropyl amide in tetrahydrofuran; hexane T=-30°C; Metallation; 1 h; 2: methyl iodide in tetrahydrofuran; hexane T=-78 - 20°C; Substitution; 3 h;
参考文献
Brimble, Margaret A.; Gorsuch, Stephen
Australian Journal of Chemistry, 1999 , vol. 52, # 10 p. 965 - 969
反应条件
sodium azide; ethanol; chloroform; sulfuric acid
参考文献
Yukawa; Tanaka
Memoirs of the Institute of Scientific and Industrial Research, Osaka University, 1957 , vol. 14, p. 199,201