(S)-(-)-3-羟基-3-苯基丙酸乙酯合成路线 （共 48 条）
反应条件
Burkholderia cepacia lipase D T=23 - 24°C; 20 h; Neat (no solvent)Enzymatic reaction;
参考文献
Tetrahedron Asymmetry, , vol. 22, # 3 p. 315 - 322
反应条件
immobilised Candida parapsilosis ATCC 7330 whole cells in ethanol; water T=25°C; 6 h;
参考文献
Tetrahedron, , vol. 62, # 21 p. 5133 - 5140
反应条件
N-((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)furan-2-carboxamide; diethylzinc in tetrahydrofuran; hexane T=0 - 20°C; Reformatsky Reaction; 1 h; Concentration; enantioselective reaction;
参考文献
Ananthi, Nallamuthu; Velmathi, Sivan
Journal of Chemical Sciences, 2014 , vol. 126, # 1 p. 151 - 158
反应条件
1: 45 percent / 0.2 M potassium phosphate buffer, EtOH, Tween 80 / 24 h / 27 °C / M. racemosus 2: 60 percent / H2, Et3N / 10percent Pd/C / ethanol / 1.5 h / 760 Torr View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 6, # 9 p. 2199 - 2210
反应条件
lt;C7H2(C2H5)2(C6H4)2C6H5gt;ClO4; hydrogen fluoride multistep reaction; other reagent, reaction time; Product distribution;
参考文献
Journal of the American Chemical Society, , vol. 119, # 46 p. 11341 - 11342
反应条件
Pseudomonas cepacia lipase immobilized on gold nanoparticles in aq. phosphate buffer T=23°C; 8 h; Resolution of racemateEnzymatic reaction; Catalytic behavior; Reagent/catalystTime;
参考文献
Journal of Molecular Catalysis B: Enzymatic, , vol. 90, p. 12 - 16
反应条件
vinyl acetate; subtilisin in di-isopropyl ether T=10 - 40°C; resolution; Thermodynamic data;
参考文献
Chemistry Letters, , # 7 p. 782 - 783
反应条件
1: With dihydrogen peroxide in chloroform T=-20°C; 16 h; 2: With N-ethyl-N,N-diisopropylamine in chloroform T=30°C; 15 h; Further stages. Title compound not separated from byproducts.;
参考文献
Tetrahedron Letters, , vol. 48, # 34 p. 5976 - 5980
反应条件
chloro-trimethyl-silane; N-aminoethyl-L-prolinol derivative; zinc in tetrahydrofuran Reformatsky reaction; 2 h; Heating;
参考文献
Shin, Eun-Kyoung; Kim, Hyun Jung; Kim, Yongtai; Kim, Yangmee; Park, Yong Sun
Tetrahedron Letters, 2006 , vol. 47, # 12 p. 1933 - 1935
反应条件
1: LDA / tetrahydrofuran 2: 6.5 h / Ambient temperature; lipase PS-30 from Pseudomonas sp. 3: 83 percent / KHCO3 / acetone / 36 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 57, # 15 p. 4289 - 4292
