(S)-(-)-3-羟基-3-苯基丙酸乙酯合成路线 （共 48 条）
反应条件
1: Cu(OH)2; (S, S)-6,6’-bis(1-hydroxy-2,2-dimethylpropyl)-2,2’-bipyridine; acetic acid / water / 12 h / 5 °C 2: sodium peroxoborate tetrahydrate / 4 h / 20 °C View Scheme
参考文献
Angewandte Chemie - International Edition, , vol. 51, # 51 p. 12763 - 12766
Angew. Chem., , vol. 124, # 51 p. 12935 - 12938
反应条件
water; trifluoroacetic acid 1.) 0 deg C, 15 min; 2.) 0 deg C, 2 h; Yield given. Multistep reaction;
参考文献
Tetrahedron, , vol. 40, # 19 p. 3769 - 3776
反应条件
1: ethanol / Einleiten von Chlorwasserstoff 2: pyridine 3: aqueous sodium nitrite; aqueous hydrochloric acid View Scheme
参考文献
Journal of the Chemical Society, , p. 1663,1666, 1668
反应条件
2: ethanol / Einleiten von Chlorwasserstoff 3: pyridine 4: aqueous sodium nitrite; aqueous hydrochloric acid View Scheme
参考文献
Journal of the Chemical Society, , p. 1663,1666, 1668
反应条件
pig liver esterase in ethanol; water T=25°C; 20 h; further solvent and time; substitution effect, enzymatic hydrolysis, also with other esters; Product distribution;
参考文献
Gazzetta Chimica Italiana, , vol. 119, # 11 p. 581 - 584
反应条件
samarium diiodide; sodium ethanolate 1.) THF, -78 deg C, 0.5 h; Multistep reaction. Title compound not separated from byproducts;
参考文献
Tetrahedron Letters, , vol. 39, # 38 p. 6899 - 6900
反应条件
lt;C7H2(CH3)2(C6H4)2C6H5gt;OTf; hydrogen fluoride multistep reaction; other reagent, reaction time; Product distribution;
参考文献
Journal of the American Chemical Society, , vol. 119, # 46 p. 11341 - 11342
反应条件
24 h; Ambient temperaturelipase Amano A, pH 7.0;
参考文献
Kumar, Ashok; Ner, D H; Dike, Suneel
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1992 , vol. 31, # 12 p. 803 - 809
参考文献
Journal of the Chemical Society, Chemical Communications, , # 23 p. 1460 - 1462
反应条件
Yield given. Multistep reaction;
参考文献
Journal of the Chemical Society, Chemical Communications, , # 23 p. 1460 - 1462
