6-羟基苯并呋喃-2-羧酸合成路线 （共 14 条）
反应条件
boron tribromide in dichloromethane T=20°C; 1 h;
参考文献
Bailly, Fabrice; Maurin, Cedric; Teissier, Elisabeth; Vezin, Herve; Cotelle, Philippe
Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 21 p. 5611 - 5618
反应条件
1: 65 percent / NaOAc; Ac2O / 8 h / 100 °C 2: 29 percent / aq. HCl / 4 h / 100 °C 3: boron tribromide / CH2Cl2 / 1 h / 20 °C View Scheme
参考文献
Bailly, Fabrice; Maurin, Cedric; Teissier, Elisabeth; Vezin, Herve; Cotelle, Philippe
Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 21 p. 5611 - 5618
反应条件
1: 29 percent / aq. HCl / 4 h / 100 °C 2: boron tribromide / CH2Cl2 / 1 h / 20 °C View Scheme
参考文献
Bailly, Fabrice; Maurin, Cedric; Teissier, Elisabeth; Vezin, Herve; Cotelle, Philippe
Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 21 p. 5611 - 5618
反应条件
1: ethanol; sodium ethylate / anschliessend Erwaermen mit wss. Kalilauge 3: hydrogen chloride; acetic acid View Scheme
参考文献
Foster et al.
Journal of the Chemical Society, 1948 , p. 2254,2258
参考文献
Karrer; Glattfelder; Widmer
Helvetica Chimica Acta, 1920 , vol. 3, p. 555
反应条件
hydrogenchloride; acetic acid
参考文献
Reichstein et al.
Helvetica Chimica Acta, 1935 , vol. 18, p. 816,826
反应条件
1: chloroform; bromine 2: alcoholic KOH-solution View Scheme
参考文献
Karrer; Glattfelder; Widmer
Helvetica Chimica Acta, 1920 , vol. 3, p. 555
反应条件
2: hydrogen chloride; acetic acid View Scheme
参考文献
Reichstein et al.
Helvetica Chimica Acta, 1935 , vol. 18, p. 816,826
反应条件
1: sodium ethylate; ethanol 2: ethanol; sodium ethylate / anschliessend Erwaermen mit wss. Kalilauge 4: hydrogen chloride; acetic acid View Scheme
参考文献
Reichstein et al.
Helvetica Chimica Acta, 1935 , vol. 18, p. 816,826
参考文献
Foster et al.
Journal of the Chemical Society, 1948 , p. 2254,2258
