1,3-二氢-3-羟基-3-(2-氧代丙基)-2H-吲哚-2-酮合成路线 （共 12 条）
反应条件
(1S)-10-camphorsulfonic acid; (1S)-1-((S)-1-methylpropyl)-(2-morpholin-4-ylethyl)amine in 1,2-dichloro-ethane T=25°C; 24 h; enantioselective reaction;
参考文献
Kumar, Akshay; Chimni, Swapandeep Singh
Beilstein Journal of Organic Chemistry, 2014 , vol. 10, p. 929 - 935
反应条件
diethylamine Heating;
参考文献
Popp; Parson; Donigan
Journal of Pharmaceutical Sciences, 1980 , vol. 69, # 10 p. 1235 - 1237
反应条件
in ethyl acetate T=20°C; Aldol Addition; 2 h; Molecular sieveSealed tube;
参考文献
Zhong, Fangrui; Jiang, Chunhui; Yao, Weijun; Xu, Li-Wen; Lu, Yixin
Tetrahedron Letters, 2013 , vol. 54, # 32 p. 4333 - 4336
反应条件
tetrabutyl ammonium fluoride; acetic acid in tetrahydrofuran T=20°C; 72 h;
参考文献
Kawasaki, Tomomi; Nagaoka, Miyuki; Satoh, Tomoko; Okamoto, Ayako; Ukon, Rie; Ogawa, Atsuyo
Tetrahedron, 2004 , vol. 60, # 15 p. 3493 - 3503
反应条件
in tetrahydrofuran T=-40 - 20°C;
参考文献
Hamashima, Yoshitaka; Suzuki, Toshiaki; Takano, Hisashi; Shimura, Yuta; Sodeoka, Mikiko
Journal of the American Chemical Society, 2005 , vol. 127, # 29 p. 10164 - 10165
反应条件
1.1: 2,6-lutidine / CH2Cl2 / 0 - 20 °C 1.2: 73 percent / AcOH / tetrahydrofuran; H2O / 5 h / 80 °C 2.1: 88 percent / O2; PdCl2; CuCl / H2O; dioxane / 5 h / 50 °C 3.1: 50 percent / n-Bu4NF; AcOH / tetrahydrofuran / 72 h / 20 °C View Scheme
参考文献
Kawasaki, Tomomi; Nagaoka, Miyuki; Satoh, Tomoko; Okamoto, Ayako; Ukon, Rie; Ogawa, Atsuyo
Tetrahedron, 2004 , vol. 60, # 15 p. 3493 - 3503
反应条件
1: 88 percent / O2; PdCl2; CuCl / H2O; dioxane / 5 h / 50 °C 2: 50 percent / n-Bu4NF; AcOH / tetrahydrofuran / 72 h / 20 °C View Scheme
参考文献
Kawasaki, Tomomi; Nagaoka, Miyuki; Satoh, Tomoko; Okamoto, Ayako; Ukon, Rie; Ogawa, Atsuyo
Tetrahedron, 2004 , vol. 60, # 15 p. 3493 - 3503
反应条件
Verb. 1 im Ueberschuss;
参考文献
Braude; Lindwall
Journal of the American Chemical Society, 1933 , vol. 55, p. 325
参考文献
Braude; Lindwall
Journal of the American Chemical Society, 1933 , vol. 55, p. 325
Full Text View citing articles Show Details
Pandalai
Justus Liebigs Annalen der Chemie, 1935 , vol. 515, p. 302,305
参考文献
Braude; Lindwall
Journal of the American Chemical Society, 1933 , vol. 55, p. 325
Full Text View citing articles Show Details
Pandalai
Justus Liebigs Annalen der Chemie, 1935 , vol. 515, p. 302,305
