2-(2-羟基苯基)吡啶合成路线 (共 27 条)
反应条件
copper diacetate; silver nitrate in 1,2,3-trichloro propane T=130°C; 24 h; Inert atmosphere;
参考文献
Zhang, Lin; Liu, Zhenhua; Li, Huiqin; Fang, Guichun; Barry, Badru-Deen; Belay, Tuemay Abadi; Bi, Xihe; Liu, Qun
Organic Letters, 2011 , vol. 13, # 24 p. 6536 - 6539
反应条件
nickel dichloride; zinc in xylene 72 h; Heating;
参考文献
Maeyama, Katsuya; Kobayashi, Masato; Yonezawa, Noriyuki
Synthetic Communications, 2001 , vol. 31, # 6 p. 869 - 875
反应条件
1: 100 percent / 1,3-bis(diphenylphosphinopropane) nickel(II) chloride / tetrahydrofuran / 0 - 20 °C 2: 41 percent / BBr3 / CH2Cl2 / -78 - 20 °C View Scheme
参考文献
Holligan, Bridget M.; Jeffery, John C.; Norgett, M. Katharine; Schatz, Erik; Ward, Michael D.
Journal of the Chemical Society, Dalton Transactions: Inorganic Chemistry (1972-1999), 1992 , # 23 p. 3345 - 3352
反应条件
copper diacetate; aniline; 1,3,5-trimethyl-benzene T=160°C; 20 h;
参考文献
Uemura, Takeshi; Imoto, Shinya; Chatani, Naoto
Chemistry Letters, 2006 , vol. 35, # 8 p. 842 - 843
反应条件
tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran 24 h; Inert atmosphereReflux;
参考文献
Kim, Seung-Hoi; Rieke, Reuben D.
Tetrahedron, 2010 , vol. 66, # 17 p. 3135 - 3146
反应条件
2,2'-azo-bisisobutyronitrile; diphenyl diselenide; tri-n-butyl-tin hydride T=95°C; 17 h;
参考文献
Crich, David; Patel, Mitesh
Tetrahedron, 2006 , vol. 62, # 33 p. 7824 - 7837
反应条件
1.1: Mg / tetrahydrofuran / 2 h / 20 °C 1.2: Ni(dppe)Cl2 / tetrahydrofuran / 12 h / 20 °C 2.1: pyridinium chloride / 3 h / 180 °C View Scheme
参考文献
Tanaka, Hiromitsu; Tokito, Shizuo; Taga, Yasunori; Okada, Akane
Journal of Materials Chemistry, 1998 , vol. 8, # 9 p. 1999 - 2003
反应条件
1.1: Mg / tetrahydrofuran / 2 h / 20 °C 1.2: Ni(dppe)Cl2 / tetrahydrofuran / 12 h / 20 °C 2.1: pyridinium chloride / 3 h / 180 °C View Scheme
参考文献
Maeyama, Katsuya; Kobayashi, Masato; Yonezawa, Noriyuki
Synthetic Communications, 2001 , vol. 31, # 6 p. 869 - 875
反应条件
1: Pd(PPh3)4; aq. Na2CO3 / toluene; ethanol / Heating 2: pyridine hydrochloride / 220 °C View Scheme
参考文献
Bishop, Michael J.; Barvian, Kevin A.; Berman, Judd; Bigham, Eric C.; Garrison, Deanna T.; Gobel, Michael J.; Hodson, Stephen J.; Irving, Paul E.; Liacos, James A.; Navas, Iii, Frank; Saussy Jr., David L.; Speake, Jason D.
Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 3 p. 471 - 475
反应条件
1: BBr3 / CH2Cl2 2: 47 percent / 0.5 h / 250 °C / in a sealed evacuated vial View Scheme
参考文献
Antkowiak, Wieslaw Z.; Gessner, Wieslaw P.
Tetrahedron Letters, 1984 , vol. 25, # 36 p. 4045 - 4048