2-(2-羟基苯基)吡啶合成路线 （共 27 条）
反应条件
2-hydroxy-1,3-isoindolinedione; oxygen; palladium dichloride in toluene T=100°C; P=760.051 Torr; 15 h; Schlenk technique; Kinetics; Overall yield = 68 percent; Overall yield = 140.2 mg;
参考文献
Yan, Yuepeng; Feng, Peng; Zheng, Qing-Zhong; Liang, Yu-Feng; Lu, Jing-Fen; Cui, Yuxin; Jiao, Ning
Angewandte Chemie - International Edition, 2013 , vol. 52, # 22 p. 5827 - 5831
Angew. Chem., 2013 , vol. 125, # 22 p. 5939 - 5943,5
反应条件
2-hydroxy-1,3-isoindolinedione; oxygen; palladium dichloride in toluene T=100°C; P=760.051 Torr; 6 h; Schlenk technique; Kinetics; Overall yield = 28 percent; Overall yield = 29.1 mg;
参考文献
Yan, Yuepeng; Feng, Peng; Zheng, Qing-Zhong; Liang, Yu-Feng; Lu, Jing-Fen; Cui, Yuxin; Jiao, Ning
Angewandte Chemie - International Edition, 2013 , vol. 52, # 22 p. 5827 - 5831
Angew. Chem., 2013 , vol. 125, # 22 p. 5939 - 5943,5
反应条件
1: 1.) sodium nitrite, HCl (1:1) / 1.) water, 80 deg C, 1 h; 2.) 80 deg C, 1 h 2: 86.1 percent / acetic acid, acetic anhydride, HI (1:1:1) / 48 h / Heating View Scheme
参考文献
Riggio, Gaetano; Hopff, Wolfgang Herbert; Hofmann, Alfred Andre; Waser, Peter Gaudenz
Helvetica Chimica Acta, 1983 , vol. 66, # 4 p. 1039 - 1045
反应条件
1: 1.) sodium nitrite, HCl (1:1) / 1.) water, 80 deg C, 1 h; 2.) 80 deg C, 1 h 2: 86.1 percent / acetic acid, acetic anhydride, HI (1:1:1) / 48 h / Heating View Scheme
参考文献
Riggio, Gaetano; Hopff, Wolfgang Herbert; Hofmann, Alfred Andre; Waser, Peter Gaudenz
Helvetica Chimica Acta, 1983 , vol. 66, # 4 p. 1039 - 1045
反应条件
T=240 - 245°C; 0.116667 h; Yields of byproduct given;
参考文献
Marshalkin, M. F.; Yakhontov, L. N.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1982 , vol. 18, # 2 p. 212
Khimiya Geterotsiklicheskikh Soedinenii, 1982 , # 2 p. 267
反应条件
Cl2Ni(1,2-bis(diphenylphosphino)ethane) Yield given;
参考文献
Cargill Thompson, Alexander M.W.; Batten, Stuart R.; Jeffery, John C.; Rees, Leigh H.; Ward, Michael D.
Australian Journal of Chemistry, 1997 , vol. 50, # 2 p. 109 - 114
反应条件
in dichloromethane 10 h; Ambient temperatureIrradiation; Yield given. Yields of byproduct given;
参考文献
Terashima, Masanao; Seki, Koh-ichi; Yoshida, Chihiro; Ohkura, Kazue; Kanaoka, Yuichi
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 3 p. 1009 - 1015
