2,2′-二吡啶基 N-氧化物合成路线 （共 35 条）
反应条件
1: 65 percent / KNO3; H2SO4 / 2.5 h / 110 °C 2: 88 percent / methanol / 0.5 h / 40 °C 3: 96 percent / POCl3 / 5 h / Heating 4: 95 percent / Pd(PPh3)4 / tetrahydrofuran / 40 h / Heating 5: 64 percent / benzeneselenic anhydride / dioxane / 24 h / Heating 6: 75 percent / hydroxylamine hydrochloride; pyridine / ethanol / 0.75 h / Heating View Scheme
参考文献
Trecourt, Francois; Gervais, Bruno; Mongin, Olivier; Gal, Catherine Le; Mongin, Florence; Queguiner, Guy
Journal of Organic Chemistry, 1998 , vol. 63, # 9 p. 2892 - 2897
反应条件
1: 41 percent / POCl3 / 12 h / Heating 2: 80 percent / KSH / dimethylformamide / 4 h / Heating View Scheme
参考文献
Wang, Fen; Schwabacher, Alan W.
Tetrahedron Letters, 1999 , vol. 40, # 26 p. 4779 - 4782
反应条件
1: 65 percent / KNO3; H2SO4 / 2.5 h / 110 °C 2: 88 percent / methanol / 0.5 h / 40 °C 3: 96 percent / POCl3 / 5 h / Heating 4: 95 percent / Pd(PPh3)4 / tetrahydrofuran / 40 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 63, # 9 p. 2892 - 2897
反应条件
1: 31 percent / 1) acetic anhydride, 2) aq. NaOH / 1) 18 h, reflux; 2) 5 h, reflux 2: 70 percent / POCl3 / 18 h / Heating 3: 76 percent / N2H4 / pyridine / 120 h / Heating 4: 79 percent / 24 h / 23 °C View Scheme
参考文献
Moran; Morton; Albright
Journal of Heterocyclic Chemistry, 1986 , vol. 23, # 4 p. 1071 - 1077
反应条件
1: With acetic anhydride; sodium hydroxide 2: in water
参考文献
Pornsuriyasak, Papapida; Rath, Nigam P.; Demchenko, Alexei V.
Chemical Communications, 2008 , # 43 p. 5633 - 5635
反应条件
hydrogen; palladium on activated charcoal in methanol 16 h;
参考文献
Plaquevent, Jean-Christophe; Chichaoui, Ilhame
Bulletin de la Societe Chimique de France, 1996 , vol. 133, # 4 p. 369 - 379
反应条件
trichlorophosphate 12 h; Heating;
参考文献
Araki, Koji; Mutai, Toshiki; Shigemitsu, Yasuhiro; Yamada, Masaki; Nakajima, Takayoshi; et al.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1996 , # 4 p. 613 - 618
反应条件
1: 31 percent / 1) acetic anhydride, 2) aq. NaOH / 1) 18 h, reflux; 2) 5 h, reflux 2: 70 percent / POCl3 / 18 h / Heating View Scheme
参考文献
Gaertner, Felix; Cozzula, Daniela; Losse, Sebastian; Boddien, Albert; Anilkumar, Gopinatan; Junge, Henrik; Schulz, Thomas; Marquet, Nicolas; Spannenberg, Anke; Gladiali, Serafino; Beller, Matthias
Chemistry - A European Journal, 2011 , vol. 17, # 25 p. 6998 - 7006
反应条件
acetyl-bromide in acetic acid 24 h; Inert atmosphereReflux;
参考文献
He, Yabing; Bian, Zheng; Kang, Chuanqing; Gao, Lianxun
Chemical Communications, 2010 , vol. 46, # 31 p. 5695 - 5697
反应条件
1: 21 percent / fuming HNO3, conc. H2SO4 / 2.5 h / Heating 2: 85 percent / NaBH4 / 5percent Pd/C / methanol 3: 1) fluoroboric acid, NaNO2 / 1) water, 2) heating View Scheme
参考文献
Nguyen, Tuan Q.; Qu, Fanqi; Huang, Xiaoling; Janzen, Alexander F.
Canadian Journal of Chemistry, 1992 , vol. 70, # 7 p. 2089 - 2093
