1: 90.8 percent / HBr / acetic acid / 0.83 h / Ambient temperature 2: 75 percent / acetic acid / tetrahydrofuran / 48 h / Ambient temperature 3: 95.3 percent / HBr / acetic acid / 0.83 h / Ambient temperature 4: 73.7 percent / acetic acid / tetrahydrofuran / 48 h / Ambient temperature 5: 93.8 percent / HBr / acetic acid / 0.83 h / Ambient temperature 6: 80 percent / acetic acid / tetrahydrofuran / 48 h / Ambient temperature 7: 60 percent / H2 / 5percent Pd/C / methanol; H2O / 24 h / 760 Torr View Scheme