1,5-二甲基-1H-吲哚-3-甲醛合成路线 （共 5 条）
参考文献
Affinium Pharmaceuticals, Inc.
Patent: EP1226138 B1, 2004 ;
反应条件
1,4-diaza-bicyclo[2.2.2]octane; oxygen; copper(II) bis(trifluoromethanesulfonate) T=100°C; P=760.051 Torr;
参考文献
Wang, Yi-Feng; Zhang, Feng-Lian; Chiba, Shunsuke
Synthesis, 2012 , vol. 44, # 10 p. 1526 - 1534
反应条件
oxygen; copper dichloride in water; dimethyl sulfoxide T=120°C; 4 h;
参考文献
Chen, Jianbin; Liu, Bin; Liu, Dongfang; Liu, Shan; Cheng, Jiang
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 13 p. 2438 - 2442
反应条件
sodium hydride in N,N-dimethyl-formamide T=0 - 20°C;
参考文献
Tripathy, Rabindranath; Ghose, Arup; Singh, Jasbir; Bacon, Edward R.; Angeles, Thelma S.; Yang, Shi X.; Albom, Mark S.; Aimone, Lisa D.; Herman, Joseph L.; Mallamo, John P.
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 6 p. 1793 - 1798
反应条件
1: POCl3 / 0 - 60 °C 2: NaH / dimethylformamide / 0 - 20 °C View Scheme
参考文献
Tripathy, Rabindranath; Ghose, Arup; Singh, Jasbir; Bacon, Edward R.; Angeles, Thelma S.; Yang, Shi X.; Albom, Mark S.; Aimone, Lisa D.; Herman, Joseph L.; Mallamo, John P.
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 6 p. 1793 - 1798
