4-(乙酰氨基)-6-氯-1,3-苯二甲酸二甲酯合成路线 （共 3 条）
反应条件
bis-triphenylphosphine-palladium(II) chloride; triethylamine in N,N-dimethyl-formamide T=80°C; P=760.051 Torr; 16 h;
参考文献
DeVita; Walsh; Young; Jiang; Ujjainwalla; Toupence; Parikh; Huang; Fair; Goulet; Wyvratt; Lo; Ren; Yudkovitz; Yang; Cheng; Cui; Mount; Rohrer; Schaeffer; Rhodes; Drisko; McGowan; MacIntyre; Vincent; Carlin; Cameron; Smith
Journal of Medicinal Chemistry, 2001 , vol. 44, # 6 p. 917 - 922
反应条件
1: I2; Ag2SO4 / methanol / 0.75 h / 20 °C 2: 93 percent / 1,2-dichloro-ethane / 3 h / 80 °C 3: 74 percent / Et3N; (PPh3)2PdCl2 / dimethylformamide / 16 h / 80 °C / 760.05 Torr View Scheme
参考文献
DeVita; Walsh; Young; Jiang; Ujjainwalla; Toupence; Parikh; Huang; Fair; Goulet; Wyvratt; Lo; Ren; Yudkovitz; Yang; Cheng; Cui; Mount; Rohrer; Schaeffer; Rhodes; Drisko; McGowan; MacIntyre; Vincent; Carlin; Cameron; Smith
Journal of Medicinal Chemistry, 2001 , vol. 44, # 6 p. 917 - 922
反应条件
1: 93 percent / 1,2-dichloro-ethane / 3 h / 80 °C 2: 74 percent / Et3N; (PPh3)2PdCl2 / dimethylformamide / 16 h / 80 °C / 760.05 Torr View Scheme
参考文献
DeVita; Walsh; Young; Jiang; Ujjainwalla; Toupence; Parikh; Huang; Fair; Goulet; Wyvratt; Lo; Ren; Yudkovitz; Yang; Cheng; Cui; Mount; Rohrer; Schaeffer; Rhodes; Drisko; McGowan; MacIntyre; Vincent; Carlin; Cameron; Smith
Journal of Medicinal Chemistry, 2001 , vol. 44, # 6 p. 917 - 922
