(2Z,4E,6Z,8E)-3,7-二甲基-9-(2,6,6-三甲基-3-氧代-1-环己烯基)壬-2,4,6,8-四烯醛合成路线 （共 28 条）
反应条件
dipyridinium dichromate in dichloromethane 1.5 h; Ambient temperature;
参考文献
Waldmann, Doris; Koenig, Thorsten; Schreier, Peter
Zeitschrift fuer Naturforschung, B: Chemical Sciences, 1995 , vol. 50, # 4 p. 589 - 594
反应条件
1: NaH / tetrahydrofuran 2: Dibal-H / diethyl ether 3: n-Bu4NF / tetrahydrofuran 4: MnO2 View Scheme
参考文献
Journal of the American Chemical Society, , vol. 119, # 24 p. 5758 - 5759
反应条件
1: Im / dimethylformamide 2: NaH / tetrahydrofuran 3: Dibal-H / diethyl ether 4: NaH / tetrahydrofuran 5: Dibal-H / diethyl ether 6: n-Bu4NF / tetrahydrofuran 7: MnO2 View Scheme
参考文献
Journal of the American Chemical Society, , vol. 119, # 24 p. 5758 - 5759
反应条件
1: NaH / tetrahydrofuran 2: Dibal-H / diethyl ether 3: NaH / tetrahydrofuran 4: Dibal-H / diethyl ether 5: n-Bu4NF / tetrahydrofuran 6: MnO2 View Scheme
参考文献
Journal of the American Chemical Society, , vol. 119, # 24 p. 5758 - 5759
反应条件
1: NaH / tetrahydrofuran 2: Dibal-H / diethyl ether 3: n-Bu4NF / tetrahydrofuran 4: MnO2 View Scheme
参考文献
Journal of the American Chemical Society, , vol. 119, # 24 p. 5758 - 5759
反应条件
1: Dibal-H / diethyl ether 2: NaH / tetrahydrofuran 3: Dibal-H / diethyl ether 4: n-Bu4NF / tetrahydrofuran 5: MnO2 View Scheme
参考文献
Journal of the American Chemical Society, , vol. 119, # 24 p. 5758 - 5759
反应条件
1.1: 67 percent / PCC; silica gel / CH2Cl2 / 4 h / 25 °C 2.1: 70 percent / n-Bu4NF / tetrahydrofuran / 0.25 h / 0 °C 3.1: 93 percent / NaBH4; CeCl3*7H2O / ethanol / 1 h / 0 °C 4.1: n-Bu3SnH; AIBN / toluene / 2.5 h / 80 °C 4.2: 71 percent / I2 / CH2Cl2 / 0.17 h / 25 °C 5.1: AsPh3 / Pd2(dba)3 / 1-methyl-pyrrolidin-2-one / 0.17 h 5.2: 67 percent / 1-methyl-pyrrolidin-2-one / 3 h / 30 °C 6.1: Dess-Martin periodinane; pyridne / CH2Cl2 / 1.5 h / 25 °C View Scheme
参考文献
Organic and Biomolecular Chemistry, , vol. 2, # 22 p. 3368 - 3373
反应条件
1.1: 70 percent / n-Bu4NF / tetrahydrofuran / 0.25 h / 0 °C 2.1: 93 percent / NaBH4; CeCl3*7H2O / ethanol / 1 h / 0 °C 3.1: n-Bu3SnH; AIBN / toluene / 2.5 h / 80 °C 3.2: 71 percent / I2 / CH2Cl2 / 0.17 h / 25 °C 4.1: AsPh3 / Pd2(dba)3 / 1-methyl-pyrrolidin-2-one / 0.17 h 4.2: 67 percent / 1-methyl-pyrrolidin-2-one / 3 h / 30 °C 5.1: Dess-Martin periodinane; pyridne / CH2Cl2 / 1.5 h / 25 °C View Scheme
参考文献
Organic and Biomolecular Chemistry, , vol. 2, # 22 p. 3368 - 3373
反应条件
1.1: n-BuLi / tetrahydrofuran; hexane / 0.5 h / 0 °C 1.2: 70 percent / tetrahydrofuran; hexane / -78 - 0 °C 2.1: 67 percent / PCC; silica gel / CH2Cl2 / 4 h / 25 °C 3.1: 70 percent / n-Bu4NF / tetrahydrofuran / 0.25 h / 0 °C 4.1: 93 percent / NaBH4; CeCl3*7H2O / ethanol / 1 h / 0 °C 5.1: n-Bu3SnH; AIBN / toluene / 2.5 h / 80 °C 5.2: 71 percent / I2 / CH2Cl2 / 0.17 h / 25 °C 6.1: AsPh3 / Pd2(dba)3 / 1-methyl-pyrrolidin-2-one / 0.17 h 6.2: 67 percent / 1-methyl-pyrrolidin-2-one / 3 h / 30 °C 7.1: Dess-Martin periodinane; pyridne / CH2Cl2 / 1.5 h / 25 °C View Scheme
参考文献
Organic and Biomolecular Chemistry, , vol. 2, # 22 p. 3368 - 3373
反应条件
1.1: n-Bu3SnH; AIBN / toluene / 2.5 h / 80 °C 1.2: 71 percent / I2 / CH2Cl2 / 0.17 h / 25 °C 2.1: AsPh3 / Pd2(dba)3 / 1-methyl-pyrrolidin-2-one / 0.17 h 2.2: 67 percent / 1-methyl-pyrrolidin-2-one / 3 h / 30 °C 3.1: Dess-Martin periodinane; pyridne / CH2Cl2 / 1.5 h / 25 °C View Scheme
参考文献
Organic and Biomolecular Chemistry, , vol. 2, # 22 p. 3368 - 3373
