(2Z,4E,6Z,8E)-3,7-二甲基-9-(2,6,6-三甲基-3-氧代-1-环己烯基)壬-2,4,6,8-四烯醛合成路线 （共 28 条）
反应条件
1.1: 93 percent / NaBH4; CeCl3*7H2O / ethanol / 1 h / 0 °C 2.1: n-Bu3SnH; AIBN / toluene / 2.5 h / 80 °C 2.2: 71 percent / I2 / CH2Cl2 / 0.17 h / 25 °C 3.1: AsPh3 / Pd2(dba)3 / 1-methyl-pyrrolidin-2-one / 0.17 h 3.2: 67 percent / 1-methyl-pyrrolidin-2-one / 3 h / 30 °C 4.1: Dess-Martin periodinane; pyridne / CH2Cl2 / 1.5 h / 25 °C View Scheme
参考文献
Organic and Biomolecular Chemistry, , vol. 2, # 22 p. 3368 - 3373
反应条件
methylamine in water; benzene 0.0833333 h; Ambient temperature;
参考文献
Acton; Brossi
Helvetica Chimica Acta, 1980 , vol. 63, # 6 p. 1391 - 1395
反应条件
pyridine; Dess-Martin periodane in dichloromethane T=25°C; Dess-Martin oxidation; 1.5 h;
参考文献
Organic and Biomolecular Chemistry, , vol. 2, # 22 p. 3368 - 3373
反应条件
pyridinium chlorochromate in dichloromethane T=0 - 25°C; 1 h; Yield given. Yields of byproduct given;
参考文献
Synthetic Communications, , vol. 13, # 11 p. 919 - 926
参考文献
Journal of the American Chemical Society, , vol. 119, # 24 p. 5758 - 5759
反应条件
pyridinium chlorochromate in dichloromethane 1 h;
参考文献
Russian Journal of Bioorganic Chemistry, , vol. 28, # 6 p. 487 - 493
反应条件
N-bromosuccinmide in dichloromethane; water; acetonitrile T=-15°C; Oxidation; 0.0833333 h; red dim light; Further byproducts given. Title compound not separated from byproducts;
参考文献
Synthetic Communications, , vol. 29, # 21 p. 3793 - 3797
反应条件
1: NBS / acetonitrile; CH2Cl2; H2O / 0.08 h / -15 °C / red dim light 2: 76 percent / MnO2 / CH2Cl2 / 2 h / 20 °C / red dim light View Scheme
参考文献
Synthetic Communications, , vol. 29, # 21 p. 3793 - 3797
反应条件
1: aq. KOAc / acetone / 24 h / 20 °C 2: 80 percent / pyridinium dichromate / CH2Cl2 / 1.5 h / Ambient temperature View Scheme
参考文献
Zeitschrift fuer Naturforschung, B: Chemical Sciences, , vol. 50, # 4 p. 589 - 594
反应条件
1: 10percent KOH / methanol / 2 h / Ambient temperature 2: 120 mg / piperidine / benzene / 4 h / Ambient temperature 3: 17 percent / pyridinium dichromate, pyridinium trifluoroacetate / CH2Cl2 / 2 h / Ambient temperature 4: 50 percent / 40percent methylamine / benzene; H2O / 0.08 h / Ambient temperature View Scheme
参考文献
Helvetica Chimica Acta, , vol. 63, # 6 p. 1391 - 1395
