反应条件
1: tetrahydrofuran / 1.) 0 deg C, 1.5 h, 2.) 25 deg C, overnight 2: H2 / 5percent Pd/C / aq. ethanol / 2327.2 Torr 3: HCl / ethanol / 1.) 25 deg C, 5 h, 2.) reflux, 1.5 h 4: K3Fe(CN)6, conc. NH4OH / H2O / 0.05 h / pH 8 View Scheme
参考文献
Reich; Fabio; Lee; Kuck; Testa
Journal of Medicinal Chemistry, 1989 , vol. 32, # 11 p. 2474 - 2485
