5-(2-呋喃基)异恶唑-3-羧酸乙酯合成路线 （共 6 条）
反应条件
hydroxylamine hydrochloride in ethanol T=85°C; 2 h;
参考文献
SK CORPORATION
Patent: WO2007/78113 A1, 2007 ;
Location in patent: Page/Page column 34; 35 ;
反应条件
hydroxylamine hydrochloride; sodium ethanolate in ethanol
参考文献
Saikachi,H.; Kitagawa,T.
Chemical and Pharmaceutical Bulletin, 1971 , vol. 19, p. 1562 - 1566
反应条件
1: sodium; diethyl ether 2: aqueous ethanol; NH2OH+HCl View Scheme
参考文献
Musante; Fatutta
Gazzetta Chimica Italiana, 1958 , vol. 88, p. 879,896
反应条件
hydrazine hydrate in water; isopropyl alcohol
参考文献
Gardner,T.S. et al.
Journal of Organic Chemistry, 1961 , vol. 26, p. 1514 - 1518
反应条件
1: With lithium hydroxide; water in tetrahydrofuran; methanol 15 h; 2: With hydrogenchloride in water
参考文献
SK CORPORATION
Patent: WO2007/78113 A1, 2007 ;
Location in patent: Page/Page column 36 ;
反应条件
sodium tetrahydroborate in ethanol
T=0 - 20°C; 4 h;
参考文献
SK CORPORATION
Patent: WO2007/78113 A1, 2007 ;
Location in patent: Page/Page column 72; 73 ;
