4,4-二溴-3-甲基-2-吡唑啉-5-酮合成路线 （共 11 条）
参考文献
El-Zohry, Maher F.; Younes, Mansour I.; Metwally, Saoud A.
Synthesis, 1984 , # 11 p. 972 - 974
反应条件
N-bromosuccinmide in dichloromethane T=20°C; 5 h;
参考文献
Jung, Jae-Chul; Blake Watkins; Avery, Mitchell A.
Heterocycles, 2005 , vol. 65, # 1 p. 77 - 94
反应条件
bromine; acetic acid T=60°C; 4 h;
参考文献
Singh, Shailendra; Husain, Kakul; Athar, Fareeda; Azam, Amir
European Journal of Pharmaceutical Sciences, 2005 , vol. 25, # 2-3 p. 255 - 262
反应条件
hydrogenchloride; sodium hydroxide 1.) ether, 1h, 0 deg C; 1h, room temp. 2.) 0 deg C; Yield given. Multistep reaction;
参考文献
van Rantwijk,F. et al.
Recueil des Travaux Chimiques des Pays-Bas, 1976 , vol. 95, p. 39 - 42
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Carpino
Journal of the American Chemical Society, 1958 , vol. 80, p. 599
反应条件
N-ethyl-N,N-diisopropylamine in dichloromethane 1.) 0 deg C, 1 h, 2.) 24 h; Further byproducts given;
参考文献
Journal of Organic Chemistry, , vol. 47, # 2 p. 207 - 213
反应条件
potassium carbonate in water; N,N-dimethyl-formamide
参考文献
Kosower,E.M.; Pazhenchevsky,B.
Journal of the American Chemical Society, 1980 , vol. 102, p. 4983
反应条件
potassium carbonate in dichloromethane
参考文献
Kosower,E.M.; Pazhenchevsky,B.
Journal of the American Chemical Society, 1980 , vol. 102, p. 4983
反应条件
N-ethyl-N,N-diisopropylamine in dichloromethane
1.) 0 deg C, 1 h, 2.) 24 h; Further byproducts given;
参考文献
Kanety, Hannah; Dodiuk, Hanna; Kosower, Edward M.
Journal of Organic Chemistry, 1982 , vol. 47, # 2 p. 207 - 213
反应条件
N-ethyl-N,N-diisopropylamine in dichloromethane
1.) 0 deg C, 1 h, 2.) 24 h; Further byproducts given;
参考文献
Kanety, Hannah; Dodiuk, Hanna; Kosower, Edward M.
Journal of Organic Chemistry, 1982 , vol. 47, # 2 p. 207 - 213
反应条件
hydrazine hydrate
6 h; Heating;
参考文献
Tewari, Ashish Kumar; Mishra, Lily; Verma; Mishra, Anil
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2002 , vol. 41, # 3 p. 664 - 667
