反应条件
1.1: CuBr*Me2S / tetrahydrofuran / 0.5 h / -78 °C
1.2: 44.31 mg / trimethylsilylchloride / tetrahydrofuran; CH2Cl2 / 1.5 h / -78 °C
2.1: diisobutylaluminum hydride / hexane; CH2Cl2 / 0.4 h / -78 °C
3.1: 2.1 g / trimethylsilyl triflate / CH2Cl2 / 0.08 h / -78 °C
4.1: methanol; trifluoroacetic acid / 20 °C
5.1: 1.92 g / triethylamine / CH2Cl2 / 1 h / 20 °C
6.1: hydrochloric acid / 42 h / 60 °C
View Scheme
参考文献
DeGoey, David A.; Chen, Hui-Ju; Flosi, William J.; Grampovnik, David J.; Yeung, Clinton M.; Klein, Larry L.; Kempf, Dale J.
Journal of Organic Chemistry, 2002 , vol. 67, # 16 p. 5445 - 5453
