5-乙氧基-2-甲基噁唑-4-羧酸合成路线 （共 7 条）
反应条件
sodium hydroxide 0.166667 h;
参考文献
Corrao, Stephanie L.; Macielag, Mark J.; Turchi, Ignatius J.
Journal of Organic Chemistry, 1990 , vol. 55, # 14 p. 4484 - 4487
反应条件
1: P2O5 / CHCl3 / Heating 2: aq. KOH / Heating View Scheme
参考文献
Sato,T.; Hino,T.
Tetrahedron, 1976 , vol. 32, p. 507 - 513
反应条件
1: oxalyl chloride, DMF / CH2Cl2 / 2 h / Ambient temperature 2: 82 percent / H2O 3: 28 percent / 2,4-bis(methoxyphenyl)-1,3-dithia-2,4-diphosphetane 2,4-disulfide (Lawesson's reagent) / tetrahydrofuran View Scheme
参考文献
Corrao, Stephanie L.; Macielag, Mark J.; Turchi, Ignatius J.
Journal of Organic Chemistry, 1990 , vol. 55, # 14 p. 4484 - 4487
反应条件
1: oxalyl chloride, DMF / CH2Cl2 / 2 h / Ambient temperature 2: 82 percent / H2O 3: 38 percent / 2,4-bis(methoxyphenyl)-1,3-dithia-2,4-diphosphetane 2,4-disulfide (Lawesson's reagent) / tetrahydrofuran View Scheme
参考文献
Corrao, Stephanie L.; Macielag, Mark J.; Turchi, Ignatius J.
Journal of Organic Chemistry, 1990 , vol. 55, # 14 p. 4484 - 4487
反应条件
oxalyl dichloride; N,N-dimethyl-formamide in dichloromethane 2 h; Ambient temperature;
参考文献
TIBOTEC PHARMACEUTICALS LTD.
Patent: WO2006/35061 A1, 2006 ;
Location in patent: Page/Page column 35 ;
反应条件
1: oxalyl chloride, DMF / CH2Cl2 / 2 h / Ambient temperature 2: 78 percent / aqueous ammonia View Scheme
参考文献
Corrao, Stephanie L.; Macielag, Mark J.; Turchi, Ignatius J.
Journal of Organic Chemistry, 1990 , vol. 55, # 14 p. 4484 - 4487
反应条件
1: oxalyl chloride, DMF / CH2Cl2 / 2 h / Ambient temperature 2: 82 percent / H2O View Scheme
参考文献
Corrao, Stephanie L.; Macielag, Mark J.; Turchi, Ignatius J.
Journal of Organic Chemistry, 1990 , vol. 55, # 14 p. 4484 - 4487
