4-(3-羟基-3-甲基-1-丁炔)苯甲酸甲酯合成路线 （共 6 条）
反应条件
pyridine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; triphenylphosphine 0.666667 h; Heating;
参考文献
Katzsch, Felix; Eissmann, Diana; Weber, Edwin
Structural Chemistry, 2012 , vol. 23, # 1 p. 245 - 255
反应条件
copper(l) iodide; (Ph3)2PdCl2; triphenylphosphine; triethylamine Sonogashira reaction; 68 h; Heating;
参考文献
Rosowsky, Andre; Forsch, Ronald A.; Sibley, Carol Hopkins; Inderlied, Clark B.; Queener, Sherry F.
Journal of Medicinal Chemistry, 2004 , vol. 47, # 6 p. 1475 - 1486
反应条件
1: sulfuric acid / 24 h / Reflux; Inert atmosphere 2: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; triethylamine; triphenylphosphine / 18 h / 50 °C / Inert atmosphere View Scheme
参考文献
Journal of Polymer Science, Part A: Polymer Chemistry, , vol. 49, # 1 p. 211 - 224
反应条件
potassium phosphate; potassium hydroxide in toluene 0.0833333 h; Inert atmosphereReflux; Reagent/catalystTime;
参考文献
Smeyanov, Alexey; Schmidt, Andreas
Synthetic Communications, 2013 , vol. 43, # 20 p. 2809 - 2816
反应条件
sodium hydroxide; tert-butyl alcohol 0.25 h; Heating;
参考文献
Percec, Virgil; Rudick, Jonathan G.; Aqad, Emad
Macromolecules, 2005 , vol. 38, # 17 p. 7205 - 7206
反应条件
1: potassium hydroxide / isopropyl alcohol / 4 h / 20 °C
2: thionyl chloride; N,N-dimethyl-formamide / chloroform / 0 - 20 °C / Inert atmosphere
View Scheme
参考文献
Pauly, Anja C.; Theato, Patrick
Journal of Polymer Science, Part A: Polymer Chemistry, 2011 , vol. 49, # 1 p. 211 - 224
