2-(4-氯苯基)-2-吗啉乙腈合成路线 （共 6 条）
反应条件
magnesium bromide T=20°C; Strecker reaction; 0.0833333 h;
参考文献
Rajabi, Fatemeh; Nourian, Saghar; Ghiassian, Sara; Balu, Alina M.; Saidi, Mohammad Reza; Serrano-Ruiz, Juan Carlos; Luque, Rafael
Green Chemistry, 2011 , vol. 13, # 11 p. 3282 - 3289
反应条件
toluene-4-sulfonic acid in tetrahydrofuran; hexane; dichloromethane; water
参考文献
US4226775 A1, ;
US 4226775 A
反应条件
perchloric acid 1) 60 deg C, 1h, 2) H2O, 90 deg C, 1 h; Multistep reaction;
参考文献
Journal of Organic Chemistry, , vol. 55, # 1 p. 58 - 63
反应条件
1: α-(4-Chlorophenyl)-4-morpholineacetonitrile With sodium hydride in N,N-dimethyl-formamide T=0°C; 0.5 h; 2: acrylic acid methyl ester in N,N-dimethyl-formamide T=0 - 20°C;
参考文献
Pawar; Waghmare; Lokhande
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2006 , vol. 45, # 11 p. 2549 - 2551
反应条件
(i) NaH, (ii) /BRN= 471606/, (iii) aq. AcOH; Multistep reaction;
参考文献
McEvoy,F.J.; Albright,J.D.
Journal of Organic Chemistry, 1979 , vol. 44, p. 4597 - 4603
反应条件
1: α-(4-Chlorophenyl)-4-morpholineacetonitrile With sodium hydride in N,N-dimethyl-formamide T=0°C; 0.5 h; 2: methacrylic acid methyl ester in N,N-dimethyl-formamide T=0 - 20°C;
参考文献
Pawar; Waghmare; Lokhande
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2006 , vol. 45, # 11 p. 2549 - 2551
