N-异丙基-4-溴苯甲酰胺合成路线 （共 5 条）
反应条件
1: 4-bromophenylacetic acid With thionyl chloride T=100°C; 1 h; Microwave irradiation; 2: isopropylamine in dichloromethane T=0°C; 1 h;
参考文献
INCYTE CORPORATION; YAO, Wenqing; BURNS, David M.; ZHUO, Jincong
Patent: WO2012/177606 A1, 2012 ;
Location in patent: Page/Page column 71 ;
WO 2012/177606 A1
反应条件
isoquinoline; potassium carbonate in acetonitrile T=20°C; 6 h;
参考文献
Alizadeh, Abdolali; Rezvanian, Atieh
Synlett, 2012 , vol. 23, # 6 art. no. ST-2011-D0298-L, p. 859 - 862
反应条件
triethylamine in dichloromethane T=0 - 20°C; Inert atmosphere;
参考文献
Organic Letters, , vol. 14, # 3 p. 906 - 909
反应条件
hydrogenchloride; zinc(II) chloride T=160°C; 72 h;
参考文献
European Journal of Organic Chemistry, , # 8 p. 1689 - 1696
反应条件
1: isopropyl alcohol With sulfuryl dichloride; PPA T=0°C; 0.0833333 h; 2: para-bromobenzonitrile T=0 - 150°C; 1 h;
参考文献
WO2004/31128 A1, ;
Page/Page column 11 ;
