1-乙酰基-5-硝基二氢吲哚合成路线 （共 11 条）
反应条件
sodium nitrate; trifluoroacetic acid 4 h; Ambient temperature;
参考文献
Mortensen, Michael B.; Kamounah, Fadhil S.; Christensen, Jorn B.
Organic Preparations and Procedures International, 1996 , vol. 28, # 1 p. 123 - 125
反应条件
anhydrous lithium nitrate; scandium tris(trifluoromethanesulfonate) in acetonitrile T=20°C; 5 h;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 50, # 8 p. 1060 - 1065
反应条件
4-(N,N-dimethlyamino)pyridine; triethylamine in dichloromethane T=0 - 20°C;
参考文献
Chemistry - A European Journal, , vol. 20, # 13 p. 3606 - 3609
反应条件
1: CHCl3 / 1 h / 20 °C 2: HNO3; Ac2O / 1 h / 20 °C View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 48, # 6 p. 817 - 827
反应条件
hydrogenchloride in ethanol; water T=5°C; Reflux;
参考文献
LUPIN LIMITED
Patent: WO2009/109999 A1, 2009 ;
Location in patent: Page/Page column 80 ;
WO 2009/109999 A1
反应条件
hydrogen; palladium on activated charcoal in methanol T=20°C; P=2585.81 Torr; 3 h;
参考文献
LUPIN LIMITED
Patent: WO2009/109999 A1, 2009 ;
Location in patent: Page/Page column 77 ;
WO 2009/109999 A1
反应条件
1: aq.-ethanolic hydrochloric acid 2: tetrachloro-<1,4>benzoquinone; xylene View Scheme
参考文献
Terent'ew et al.
Zhurnal Obshchei Khimii, 1959 , vol. 29, p. 2541,2550; engl. Ausg. S. 2504, 2511
反应条件
sodium hydroxide; aluminium-nickel alloy in water 1.5 h;
参考文献
Salekh, M.A.; Kurkovskaya, L.N.; Krasavina, L.S.; Persianova,I.V.; Vigdorchik, M.M.; Suvorov, N.N.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1988 , p. 624 - 627
Khimiya Geterotsiklicheskikh Soedinenii, 1988 , vol. 24, # 6 p. 766 - 769
反应条件
1: aq.-ethanolic hydrochloric acid
2: acetic acid; bromine
3: acetyl chloride; acetic acid
4: platinum; ethanol / Hydrogenation
View Scheme
参考文献
Gall et al.
Journal of Organic Chemistry, 1955 , vol. 20, p. 1538,1541
反应条件
1: aq.-ethanolic hydrochloric acid
2: acetic acid; bromine
View Scheme
参考文献
Gall et al.
Journal of Organic Chemistry, 1955 , vol. 20, p. 1538,1541
