hydrogen; palladium on activated charcoal in ethanol 20 h;

1: DBU / acetonitrile / 4 h / Heating 2: H2 / 5percent Pd/C / ethanol / 20 h View Scheme

1: 95 percent / acetonitrile / 5 h / Heating 2: DBU / acetonitrile / 4 h / Heating 3: H2 / 5percent Pd/C / ethanol / 20 h View Scheme

hydrogen; palladium on activated charcoal P=1551.4 Torr;

1.1: 2,2,6,6-tetramethyl-piperidine; n-butyllithium; potassium tert-butylate / tetrahydrofuran / 0.25 h / -78 °C / Inert atmosphere 1.2: -78 - 20 °C / Inert atmosphere 2.1: hydrogenchloride / methanol; water / Reflux View Scheme

n-butyllithium; potassium tert-butylate 1.) hexane, reflux, 3 h, 2.) THF; Yield given. Multistep reaction;