3-溴-1-甲基吡咯烷-2-酮合成路线 （共 5 条）
反应条件
sodium hydride in tetrahydrofuran T=10 - 15°C;
参考文献
AstraZeneca AB
Patent: US2008/171734 A1, 2008 ;
Location in patent: Page/Page column 37 ;
US 20080171734 A1
反应条件
sodium hydrogen sulphate; N-bromosuccinmide; silica gel T=80°C; 3 h;
参考文献
Das, Biswanath; Venkateswarlu, Katta; Mahender, Gurram; Mahender, Ibram
Tetrahedron Letters, 2005 , vol. 46, # 17 p. 3041 - 3044
反应条件
sodium hydroxide; MeNH2; NaH; sodium chloride in chloroform; water; toluene
参考文献
Farina; Carlo; Nadler; Guy Marguerite Marie Gerard; Seneci; Pierfausto
Patent: US5985905 A1, 1999 ;
反应条件
indium; water T=20°C; 6 h;
参考文献
Park, Leeyoung; Keum, Gyochang; Kang, Soon Bang; Kim, Kwan Soo; Kim, Youseung
Journal of the Chemical Society, Perkin Transactions 1, 2000 , # 24 p. 4462 - 4463
反应条件
18-crown-6 ether in acetonitrile
参考文献
Kamal, Ahmed; Ramana, K. Venkata; Ramana, A. Venkata; Babu, A. Hari
Tetrahedron Asymmetry, 2003 , vol. 14, # 17 p. 2587 - 2594
