1,2-二氢-1-吡啶羧酸甲酯合成路线 （共 15 条）
反应条件
sodium tetrahydroborate in methanol T=-78°C; 1 h;
参考文献
Abou-Jneid, Robert; Ghoulami, Said; Martin, Marie-Therese; Dau, Elise Tran Huu; Travert, Nathalie; Al-Mourabit, Ali
Organic Letters, 2004 , vol. 6, # 22 p. 3933 - 3936
反应条件
NH4Br T=90 - 100°C; P=70 - 100 Torr; 2 h;
参考文献
Shono, Tatsuya; Matsumura, Yoshihiro; Onomura, Osamu; Yamada, Yasufu
Tetrahedron Letters, 1987 , vol. 28, # 35 p. 4073 - 4074
反应条件
sodium tetrahydroborate in methanol; diethyl ether T=-78°C; 2 h; Title compound not separated from byproducts;
参考文献
Baguley, Paul A.; Walton, John C.
Journal of the Chemical Society. Perkin Transactions 2, 1998 , # 6 p. 1423 - 1429
反应条件
1: 2.) NH4Cl / 1.) -2e, MeOH, 2.) heating 2: 80 percent / NaOMe, Br2 / Ambient temperature 3: 77 percent / electrochem. generated 2-pyrrolidine anion / dimethylformamide / Ambient temperature; further base 4: 65 percent / NH4Br / 2 h / 90 - 100 °C / 70 - 100 Torr View Scheme
参考文献
Tetrahedron Letters, , vol. 28, # 35 p. 4073 - 4074
反应条件
1: 80 percent / NaOMe, Br2 / Ambient temperature 2: 77 percent / electrochem. generated 2-pyrrolidine anion / dimethylformamide / Ambient temperature; further base 3: 65 percent / NH4Br / 2 h / 90 - 100 °C / 70 - 100 Torr View Scheme
参考文献
Tetrahedron Letters, , vol. 28, # 35 p. 4073 - 4074
反应条件
1: 77 percent / electrochem. generated 2-pyrrolidine anion / dimethylformamide / Ambient temperature; further base 2: 65 percent / NH4Br / 2 h / 90 - 100 °C / 70 - 100 Torr View Scheme
参考文献
Tetrahedron Letters, , vol. 28, # 35 p. 4073 - 4074
参考文献
Kumagai, Tsutomu; Saito, Shue; Ehara, Takashi
Tetrahedron Letters, 1991 , vol. 32, # 47 p. 6895 - 6898
反应条件
pyrolysis in an apparatus described in J.Am.Chem.(19)Soc83, 105, 7696;
参考文献
Wyle, Michael J.; Fowler, Frank W.
Journal of Organic Chemistry, 1984 , vol. 49, # 21 p. 4025 - 4029
反应条件
1: 55 percent / anhydrous potassium carbonate / 30 h / Ambient temperature 2: 43 percent / pyrolysis in an apparatus described in J.Am.Chem.(19)Soc83, 105, 7696 View Scheme
参考文献
Journal of Organic Chemistry, , vol. 49, # 21 p. 4025 - 4029
反应条件
in hexane T=60°C; Irradiation;
参考文献
Tetrahedron Letters, , vol. 32, # 47 p. 6895 - 6898
