1: H2O2, DCC 2: Cu(OAc)2*H2O, Cu2O, AcOH / acetonitrile View Scheme

copper(I) oxide; copper diacetate; acetic acid in acetonitrile

(i) LiAlH4, (ii) /BRN= 605303/; Multistep reaction;

1: 1.) AlCl3 2.)PCl5 / 1.) CS2, 0 deg C, 2.) phosphorus oxychloride, 40 to 45 deg C, 2.5 h 2: 93 percent / KOH / methanol; H2O / 0.17 h 3: 91 percent / lithium diisopropylamide / tetrahydrofuran / 1 h / Ambient temperature 4: 1.) n-butyllithium / 1.)THF, hexane, -78 degC 2.) room temperature, overnight 5: 80 percent / triphenylphosphine dibromide, collidine / CH2Cl2 / 5 h / Ambient temperature View Scheme