2-溴甲基-1-苯磺酰基-1h-吲哚合成路线 （共 3 条）
反应条件
sulfuric acid; hydrogen bromide in dichloromethane 1.5 h;
参考文献
De Dios, Alfonso; Prieto, Lourdes; Martin, Jose Alfredo; Rubio, Almudena; Ezquerra, Jesus; Tebbe, Mark; Lopez De Uralde, Beatriz; Martin, Justina; Sanchez, Ana; LeTourneau, Deborah L.; McGee, James E.; Boylan, Carole; Parr Jr., Thomas R.; Smith, Michele C.
Journal of Medicinal Chemistry, 2002 , vol. 45, # 20 p. 4559 - 4570
反应条件
1.1: n-BuLi / tetrahydrofuran / 1 h / -78 °C 1.2: tetrahydrofuran / 2 h / -78 °C 2.1: DIBAL-H / tetrahydrofuran; hexane / 1 h / -78 °C 3.1: aq. HBr; H2SO4 / CH2Cl2 / 1.5 h View Scheme
参考文献
De Dios, Alfonso; Prieto, Lourdes; Martin, Jose Alfredo; Rubio, Almudena; Ezquerra, Jesus; Tebbe, Mark; Lopez De Uralde, Beatriz; Martin, Justina; Sanchez, Ana; LeTourneau, Deborah L.; McGee, James E.; Boylan, Carole; Parr Jr., Thomas R.; Smith, Michele C.
Journal of Medicinal Chemistry, 2002 , vol. 45, # 20 p. 4559 - 4570
反应条件
1: DIBAL-H / tetrahydrofuran; hexane / 1 h / -78 °C 2: aq. HBr; H2SO4 / CH2Cl2 / 1.5 h View Scheme
参考文献
De Dios, Alfonso; Prieto, Lourdes; Martin, Jose Alfredo; Rubio, Almudena; Ezquerra, Jesus; Tebbe, Mark; Lopez De Uralde, Beatriz; Martin, Justina; Sanchez, Ana; LeTourneau, Deborah L.; McGee, James E.; Boylan, Carole; Parr Jr., Thomas R.; Smith, Michele C.
Journal of Medicinal Chemistry, 2002 , vol. 45, # 20 p. 4559 - 4570
