4-[[(4-氟苯基)亚胺]甲基]-苯酚合成路线 （共 2 条）
反应条件
in isopropyl alcohol T=50°C; 1 h;
参考文献
SCHERING CORPORATION
Patent: EP1137634 B1, 2005 ;
Location in patent: Page/Page column 9 ;
反应条件
1: chloro-trimethyl-silane; 4-fluoro-N-(4-hydroxyphenyl)methylene-benzenamine; (S)-3-[5-(4-fluorophenyl)-5(S)-hydroxy-pentanoyl]-4-phenyl-oxazolidin-2-one With N-ethyl-N,N-diisopropylamine in dichloromethane T=-10 - -5°C; 1 h; 2: With titanium tetrachloride in dichloromethane T=-30°C; 20 h; 3: N,O-bis-(trimethylsilyl)-acetamide
参考文献
WO2012/4382 A1, ;
Page/Page column 25 ;
