4,6-二甲基-2-氧-2H-吡喃-5-甲酸乙酯合成路线 （共 36 条）
反应条件
1: 20 percent / benzophenone / acetonitrile / 5 h / Ambient temperature; Irradiation
2: 54 percent / 1,8-diazabicyclo<5.4.0>undec-7-ene (DBU) / 24 h / Ambient temperature
View Scheme
参考文献
Shimo, Tetsuro; Date, Kenichi; Somekawa, Kenichi
Journal of Heterocyclic Chemistry, 1992 , vol. 29, # 2 p. 387 - 390
参考文献
Wiley et al.
Journal of the American Chemical Society, 1954 , vol. 76, p. 311
反应条件
1: 95 percent / NaOH / H2O / 1 h / 70 °C
2: 85 percent / Ac2O / 0.5 h / 70 °C
3: 41 percent / pyridine / 1 h / 25 °C
View Scheme
参考文献
Jung; Lowe III; Lyster; et al.
Tetrahedron, 1984 , vol. 40, # 22 p. 4751 - 4766
反应条件
1: 95 percent / NaOH / H2O / 1 h / 70 °C
2: 85 percent / Ac2O / 0.5 h / 70 °C
View Scheme
参考文献
Cornforth, John; Hawes, John E.; Mallaby, Richard
Australian Journal of Chemistry, 1992 , vol. 45, # 1 p. 179 - 185
反应条件
1: 95 percent / NaOH / H2O / 1 h / 70 °C
2: 85 percent / Ac2O / 0.5 h / 70 °C
3: 80 percent / diethyl ether / 12 h / 25 °C
4: 2.) Ag2O, MgSO4 / 1.) xylene, reflux, 5 d; 2.) RT, 12 h
View Scheme
参考文献
Jung; Lowe III; Lyster; et al.
Tetrahedron, 1984 , vol. 40, # 22 p. 4751 - 4766
反应条件
1: Na-OEt / ethanol
2: 67 percent / ethanol
View Scheme
参考文献
Quast, Helmut; Berneth, Claus-Peter
Chemische Berichte, 1983 , vol. 116, # 4 p. 1345 - 1363
反应条件
in toluene
distillation to 200 deg C;
参考文献
Gingrich, Henry L.; Roush, David M.; Saun, William A. Van
Journal of Organic Chemistry, 1983 , vol. 48, # 25 p. 4869 - 4873
参考文献
Gingrich, Henry L.; Roush, David M.; Saun, William A. Van
Journal of Organic Chemistry, 1983 , vol. 48, # 25 p. 4869 - 4873
反应条件
1: nitric acid
2: acetic acid
View Scheme
参考文献
Panizzi
Gazzetta Chimica Italiana, 1942 , vol. 72, p. 423,428
反应条件
ethanol
diethyl ester of/the/ lower-melting 3-methyl-pentenedioic acid;
参考文献
Henrick; Willy; Baum; et al.
Journal of Organic Chemistry, 1975 , vol. 40, # 1 p. 1 - 7
