1.1: 63 percent / DIBAL-H / toluene; hexane / 3 h / -78 °C 2.1: K2CO3 / methanol / 1 h / Heating 2.2: 82 percent / KOH / methanol / 6 h / Heating 3.1: 90 percent / 1,2-dichloro-benzene / 20 h / Heating 4.1: Et3N; CF3CH2OH / 72 h / 20 °C 4.2: 73 percent / Zn; NH4Cl / methanol / 10 h / 20 °C / sonication 5.1: 83 percent / PhI(OAc)2; KOH / 12 h / 20 °C 6.1: 96 percent / aq. AcOH / 8 h / 20 °C 7.1: 62 percent / TMSOTf; Et3N / CH2Cl2 / 1 h / 10 °C 8.1: 34 percent / MeOH / tetrahydrofuran; hexane / 48 h / 20 °C View Scheme