甲基(2E,4E,6E,8E)-3,7-二甲基-9-(2,6,6-三甲基-1-环己烯基)壬-2,4,6,8-四烯酸酯合成路线 （共 32 条）
反应条件
tris(dibenzylideneacetone)dipalladium (0); triphenyl-arsane in various solvent(s) T=60°C; Substitution; 0.5 h;
参考文献
Dominguez, Beatriz; Iglesias, Beatriz; De Lera, Angel R.
Tetrahedron, 1999 , vol. 55, # 52 p. 15071 - 15098
反应条件
in methanol; hexane; benzene T=20°C; 0.75 h;
参考文献
Patel, Jyoti B.; Huynh, Carlic K.; Handratta, Venkatesh D.; Gediya, Lalji K.; Brodie, Angela M. H.; Goloubeva, Olga G.; Clement, Omoshile O.; Nanne, Ivo P.; Soprano, Dianne Robert; Njar, Vincent C. O.
Journal of Medicinal Chemistry, 2004 , vol. 47, # 27 p. 6716 - 6729
反应条件
tris(dibenzylideneacetone)dipalladium (0); triphenyl-arsane in various solvent(s) T=50°C; Alkylation; 3 h;
参考文献
Dominguez, Beatriz; Iglesias, Beatriz; De Lera, Angel R.
Tetrahedron, 1999 , vol. 55, # 52 p. 15071 - 15098
反应条件
potassium carbonate; butanone
参考文献
Raghavan, N.V.; Das, P.K.; Bobrowski, K.
Journal of the American Chemical Society, 1981 , vol. 103, # 15 p. 4569 - 4573
反应条件
tris(dibenzylideneacetone)dipalladium (0); triphenyl-arsane in various solvent(s) T=60°C; Alkylation; 3 h;
参考文献
Dominguez, Beatriz; Iglesias, Beatriz; De Lera, Angel R.
Tetrahedron, 1999 , vol. 55, # 52 p. 15071 - 15098
反应条件
dicyclohexyl-carbodiimide in diethyl ether 1.) 0 deg C, 30 min, 2.) 25 deg C, 1 h;
参考文献
Singh, Anil K.
Synthetic Communications, 1982 , vol. 12, # 6 p. 447 - 452
反应条件
potassium cyanide; manganese(IV) oxide; acetic acid in methanol 12 h; Ambient temperature;
参考文献
Pardoen, J. A; Winkel, C; Mulder, P.P.J; Lugtenburg, J
Recueil: Journal of the Royal Netherlands Chemical Society, 1984 , vol. 103, # 4 p. 135 - 141
反应条件
1: SOCl2 / toluene; pyridine / 20 °C 2: 182 mg / toluene; pyridine / 2 h / 20 °C View Scheme
参考文献
Wong, Corinne G.; Rando, Robert R.
Journal of the American Chemical Society, 1982 , vol. 104, # 25 p. 7374 - 7375
反应条件
1: 80 percent / n-butyllithium / tetrahydrofuran; hexane / 1 h / 0 °C 2: 100 percent / 4-(dimethyilamino)pyridine / toluene / 20 h / Ambient temperature 3: 93 percent / DBN / toluene / 1.5 h / Heating 4: 95 percent / Diisobuthylaluminium hydride / petroleum ether; hexane / 1 h / -60 - -20 °C 5: 98 percent / KCN, MnO2, AcOH / methanol / 12 h / Ambient temperature View Scheme
参考文献
Karrer; Jucker; Schick
Helvetica Chimica Acta, 1946 , vol. 29, p. 704,710
反应条件
in pyridine; toluene T=20°C; 2 h;
参考文献
Fungo, Fernando; Otero, Luis; Durantini, Edgardo; Thompson, William J.; Silber, Juana J.; Moore, Thomas A.; Moore, Ana L.; Gust, Devens; Sereno, Leonides
Physical Chemistry Chemical Physics, 2003 , vol. 5, # 3 p. 469 - 475
