4-(三氟甲基)亚苯基肼合成路线 (共 13 条)
反应条件
toluene-4-sulfonic acid
T=90 - 120°C; 2 h; Neat (no solvent); Product distribution / selectivity;
参考文献
ELI LILLY AND COMPANY
Patent: WO2005/65683 A1, 2005 ;
Location in patent: Page/Page column 84-85; 101; 111 ;
WO 2005/065683 A1
反应条件
T=140°C; 8 h; Inert atmosphere;
参考文献
Kawano, Tsuyoshi; Hirano, Koji; Satoh, Tetsuya; Miura, Masahiro
Journal of the American Chemical Society, 2010 , vol. 132, # 20 p. 6900 - 6901
反应条件
potassium hydroxide in ethanol
Heating;
参考文献
Yan, Xu; Zhou, Shuo; Wang, Yuanqiang; Ge, Zemei; Cheng, Tieming; Li, Runtao
Tetrahedron, 2012 , vol. 68, # 38 p. 7978 - 7983