1-(4-氯苯基)乙醇合成路线 （共 156 条）
反应条件
Arthrobacter atrocyaneus in N,N-dimethyl-formamide T=32°C; 72 h; Microbiological reaction; enantioselective reaction;
参考文献
Silva, Camila R.; Souza, Juliana C.; Araujo, Lidiane S.; Kagohara, Edna; Garcia, Thais P.; Pelizzari, Vivian H.; Andrade, Leandro H.
Journal of Molecular Catalysis B: Enzymatic, 2012 , vol. 83, p. 23 - 28
反应条件
in water 24 h; Geotrichum candidum IFO 5767, without and with allyl alcohol as an additive; Product distribution;
参考文献
Gong, Yinhan; Lee, Hian Kee
Analytical Chemistry, 2003 , vol. 75, # 6 p. 1348 - 1354
反应条件
polyoxyethylene (10) cetyl ether; n-octyl beta-D-glucopyranoside; subtilisin Carlsberg; sodium carbonate in tetrahydrofuran T=20°C; 15 h; Title compound not separated from byproducts;
参考文献
Boren, Linnea; Martin-Matute, Belen; Xu, Yongmei; Cordova, Armando; Baeckvall, Jan-E.
Chemistry - A European Journal, 2006 , vol. 12, # 1 p. 225 - 232
反应条件
[(C4Ph4COHOCC4Ph4)(μ-H)][(CO)4Ru2]; Novozym(R) 435; 2,4-dimethylpentan-3-one in toluene T=70°C; P=142.511 Torr; 40 h;
参考文献
Verzijl, Gerard K.M.; De Vries, Johannes G.; Broxterman, Quirinus B.
Tetrahedron Asymmetry, 2005 , vol. 16, # 9 p. 1603 - 1610
反应条件
Pseudomonas cepacia lipase in di-isopropyl ether T=30°C; Esterification; Racemate separation; 14 h;
参考文献
Athawale, Vilas; Manjrekar, Narendra
Synlett, 2000 , # 2 p. 225 - 226
反应条件
M. esculenta enzyme preparation immobilized on alginate gel in diethyl ether T=45°C; 116 h;
参考文献
Netto, Caterina G.C.M.; Andrade, Leandro H.; Toma, Henrique E.
Tetrahedron Asymmetry, 2009 , vol. 20, # 19 p. 2299 - 2304
反应条件
aluminium trichloride in hexane; toluene T=-5°C; 17 h; Title compound not separated from byproducts;
参考文献
Kashima, Choji; Mizuhara, Saori; Miwa, Yohei; Yokoyama, Yukihiro
Tetrahedron Asymmetry, 2002 , vol. 13, # 16 p. 1713 - 1719
反应条件
1: α-methyl-4-chlorobenzyl alcohol With (S,R(P))-2-phenyl-2,3-dihydroimidazo[1,2-a]pyrindinyl-pentaphenylcyclopentadienyliron; N-ethyl-N,N-diisopropylamine in toluene T=0°C; 0.0833333 h; 2: propionic acid anhydride in toluene T=0°C; 8 h; optical yield given as percent eeenantioselective reaction;
参考文献
Hu, Bin; Meng, Meng; Wang, Zheng; Du, Wenting; Fossey, John S.; Hu, Xinquan; Deng, Wei-Ping
Journal of the American Chemical Society, 2010 , vol. 132, # 47 p. 17041 - 17044
反应条件
steapsin lipase in hexane T=55°C; 48 h; Enzymatic reaction; optical yield given as percent ee;
参考文献
Dhake, Kishor P.; Deshmukh, Krishna M.; Wagh, Yogesh S.; Singhal, Rekha S.; Bhanage, Bhalchandra M.
Journal of Molecular Catalysis B: Enzymatic, 2012 , vol. 77, p. 15 - 23
反应条件
1: triethylamine / dichloromethane / 0 °C 2: Lipase Amano AK / 32 h / 20 °C / pH 7 / aq. phosphate buffer; Enzymatic reaction View Scheme
参考文献
Bora, Pranjal P.; Bez, Ghanashyam; Anal, Jasha Momo H.
Journal of Molecular Catalysis B: Enzymatic, 2011 , vol. 72, # 3-4 p. 270 - 275
