1: trans-3-[4-acetyloxy-3-methoxyphenyl]-2-propenoic acid With N-bromosuccinmide; anhydrous lithium acetate in ethylene glycol dimethyl ether; water T=100°C; Hunsdiecker bromodecarboxylation; 0.0166667 h; microwave irradiation; 2: 3,4,5-trimethoxyphenylboronic acid With sodium hydroxide; tetrakis(triphenylphosphine) palladium(0) in ethylene glycol dimethyl ether; water T=100°C; Suzuki cross-coupling; 0.166667 h; Further stages.;

tetrabutyl ammonium fluoride in tetrahydrofuran; diethyl ether T=0°C; Substitution; 20 h;

AlCl3, aluminium chloride in 1,4-dioxane T=80°C; 8 h; stereoselective reaction;

piperidine; 1-methyl-1H-imidazole in various solvent(s) T=160°C; 0.166667 h; microwave irradiation;

1: With sodium tetrahydroborate in ethanol 1 h; Heating; 2: With hydrogenchloride in ethanol 5 h; Heating;

AlCl3, aluminium chloride in 1,4-dioxane T=80°C; 8 h; stereoselective reaction;

sodium hydride in tetrahydrofuran T=0°C; Wittig reaction;

1: phenylmethylphosphonic acid,diethyl ester With 18-crown-6 ether; sodium methylate in N,N-dimethyl-formamide T=20°C; 0.0833333 h; 2: (4-formyl-2-methoxyphenoxy)methoxymethane in N,N-dimethyl-formamide T=20 - 120°C; Horner-Emmons-Wadsworth reaction; 6 h; 3: With hydrogenchloride; methanol Heating;

1-methyl-1H-imidazole; sodium hydrogencarbonate 0.333333 h; Heatingmicrowave irradiation;

1-methyl-1H-imidazole; sodium hydrogencarbonate 0.333333 h; Heatingmicrowave irradiation;