反应条件
1: iodobenzene With n-butyllithium; zinc dibromide in tetrahydrofuran; hexane
T=-78 - 20°C;
2: 2-iodo-2-cyclopent-2-en-1-one With bis-triphenylphosphine-palladium(II) chloride; n-butyllithium in tetrahydrofuran; hexane; N,N-dimethyl-formamide
T=20°C; Negishi coupling; 5 h;
参考文献
Pour, Milan; Spulak, Marcel; Balsanek, Vojtech; Kunes, Jiri; Kubanova, Petra; Buchta, Vladimir
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 13 p. 2843 - 2866
