1,2-二甲氧基-4-二硝基苯合成路线 （共 69 条）
参考文献
Parijs
Recueil des Travaux Chimiques des Pays-Bas, 1929 , vol. 48, p. 561
反应条件
1: H2 / Pd/C
2: 95 percent / POCl3
View Scheme
参考文献
He, Wei; Myers, Michael R.; Hanney, Barbara; Spada, Alfred P.; Bilder, Glenda; Galzcinski, Helen; Amin, Dilip; Needle, Saul; Page, Ken; Jayyosi, Zaid; Perrone, Mark H.
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 18 p. 3097 - 3100
反应条件
hydrogen; palladium on activated charcoal
参考文献
Baudy, Reinhardt B.; Greenblatt, Lynne P.; Jirkovsky, Ivo L.; Conklin, Mary; Russo, Ralph J.; et al.
Journal of Medicinal Chemistry, 1993 , vol. 36, # 3 p. 331 - 342
反应条件
palladium monocarbide in methanol
参考文献
Hoechst Aktiengesellschaft; Genetech, Inc.
Patent: US6218415 B1, 2001 ;
反应条件
sodium sulfide; ethanol
参考文献
Nandi
Current Science, 1940 , vol. 9, p. 118
参考文献
Moureu
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1897 , vol. 125, p. 33
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Heinisch
Monatshefte fuer Chemie, 1894 , vol. 15, p. 233
参考文献
Nandi
Current Science, 1940 , vol. 9, p. 118
参考文献
Oliverio
Gazzetta Chimica Italiana, 1943 , vol. 73, p. 181,196
反应条件
(i) H2, Raney-Ni, AcOEt, xylene, (ii) /BRN= 5413887/, (iii) AcOH; Multistep reaction;
参考文献
Werner; Jungstand; Gutsche; Wohlrabe; Roemer; Tresselt
Pharmazie, 1979 , vol. 34, # 7 p. 394 - 397
反应条件
1: H2 / Raney nickel / ethanol / 30 h / 20 °C
2: KOH / ethanol / 10 h / Heating
3: 71.2 percent / NaOC2H5 / ethanol / 2.5 h / Heating
View Scheme
参考文献
Krutovskikh, G. N.; Gornaeva, G. F.; Krivozheiko, K. M.; Girshovich, M. Z.; Varmanyan, L. P.; El'tsov, A. V.
Pharmaceutical Chemistry Journal, 1980 , vol. 14, # 2 p. 130 - 133
Khimiko-Farmatsevticheskii Zhurnal, 1980 , vol. 14, # 5 p. 58 - 61
