[(噻吩-2-羰基)氨基]乙酸合成路线 （共 5 条）
反应条件
1: glycine With sodium hydroxide in water 2: 2-thiophenoyl chloride With sodium hydroxide in water T=5 - 12°C; pH=Ca. 10; 1.5 h; 3: With hydrogenchloride in water pH=2;
参考文献
Regberg, Tor; Lindquist, Charlotta; Pilotti, Ake; Ellstroem, Christel; Faegerstam, Lars; Eckersten, Ann; Shinohara, Yasuro; Gallion, Steven L.; Hogan Jr., Joseph C.
Combinatorial Chemistry and High Throughput Screening, 2011 , vol. 14, # 4 p. 267 - 278
反应条件
1: thiophene-2-carboxylic acid With pyridine; thionyl chloride T=110°C; 2 h; 2: glycine With sodium hydroxide in water T=20°C; 0.5 h;
参考文献
Gucky, Tomas; Slouka, Jan; Malon, Michal; Frysova, Iveta
Journal of Heterocyclic Chemistry, 2006 , vol. 43, # 3 p. 613 - 621
参考文献
Jaffe; Levy
Chemische Berichte, 1888 , vol. 21, p. 3458
参考文献
Jaffe; Levy
Chemische Berichte, 1888 , vol. 21, p. 3458
反应条件
sodium acetate in acetic acid
参考文献
Krasovitskii,B.M. et al.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1979 , vol. 15, p. 1303 - 1306
Khimiya Geterotsiklicheskikh Soedinenii, 1979 , vol. 15, # 12 p. 1624 - 1627
