反应条件
1: triphenylphosphine dibromide / CH2Cl2 2: 1.) magnesium ethoxide / 1.) ethanol, reflux, 1 h; 2.) reflux, 18 h 3: 1.) NaH, 2.) 15percent aq. NaOH / 1.) DME, r.t., 1 h; reflux, 18 h, 2.) reflux, 20 h 4: 38 percent / p-toluenesulfonylhydrazine, p-toluenesulfonic acid, sodium cyanoborohydride / dimethylformamide; tetrahydrothiophene 1,1-dioxide / 4 h / 100 °C 5: LiAlH4 / diethyl ether / 1.) r.t., 1 h, 2.) reflux, 1 h View Scheme
参考文献
Agricultural and Biological Chemistry, , vol. 44, # 6 p. 1419 - 1420
