N-苄氧羰基-L-苯丙氨酸，N-羟基琥珀酰亚胺酯合成路线 （共 16 条）
反应条件
triethylamine in tetrahydrofuran; water T=24°C; 0.5 h;
参考文献
Sosnovsky; Prakash; Rao
Journal of Pharmaceutical Sciences, 1993 , vol. 82, # 1 p. 1 - 10
反应条件
1: H2O; tetrahydrofuran / 48 h / Ambient temperature 2: H2 View Scheme
参考文献
Suzuki; Fujita; Sasaki; Shiratori; Sakurada; Kisara
Chemical and Pharmaceutical Bulletin, 1988 , vol. 36, # 12 p. 4834 - 4840
反应条件
1: 91 percent / dimethylformamide / 12 h / 20 °C 2: H2 / 5percent Pd/C / ethanol View Scheme
参考文献
Sidorova, M. V.; Kudryavtseva, E. V.; Molokoedov, A. S.; Ovchinnikov, M. V.; Bespalova, Zh. D.
Russian Journal of Bioorganic Chemistry, 1995 , vol. 21, # 9 p. 582 - 589
Bioorganicheskaya Khimiya, 1995 , vol. 21, # 9 p. 675 - 685
反应条件
N-ethyl-N,N-diisopropylamine in ethyl acetate
T=20°C;
参考文献
Fransson, Rebecca; Botros, Milad; Skoeld, Christian; Nyberg, Fred; Lindeberg, Gunnar; Hallberg, Mathias; Sandstroem, Anja
Journal of Medicinal Chemistry, 2010 , vol. 53, # 6 p. 2383 - 2389
反应条件
triethylamine in tetrahydrofuran; water
7 h; Ambient temperature;
参考文献
Kouge; Koizumi; Okai; Kato
Bulletin of the Chemical Society of Japan, 1987 , vol. 60, # 7 p. 2409 - 2418
反应条件
1: 82 percent / TEA / H2O; acetonitrile / 20 h / Ambient temperature
2: 88 percent / H2 / Pd / acetic acid; methanol; H2O
View Scheme
参考文献
Ienaga; Higashiura; Kimura
Chemical and pharmaceutical bulletin, 1987 , vol. 35, # 3 p. 1249 - 1254
