1-甲基-2-氧代-1,2-二氢吡啶-4-羧酸合成路线 （共 23 条）
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 6, p. 615,617
反应条件
1: toluene-4-sulfonic acid; benzene 2: anschliessende Oxidation mit K3<Fe(CN)6> 3: water; hydrochloric acid 4: Ag2O; H2O View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 6, p. 615,617
反应条件
1: anschliessende Oxidation mit K3<Fe(CN)6> 2: water; hydrochloric acid 3: Ag2O; H2O View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 6, p. 615,617
反应条件
1: water; hydrochloric acid 2: Ag2O; H2O View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 6, p. 615,617
反应条件
1: water; hydrochloric acid 2: aqueous NaOBr View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 6, p. 615,617
反应条件
potassium chloride; water T=25°C; Rate constant;
参考文献
Australian Journal of Chemistry, , vol. 38, # 4 p. 637 - 641
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 6, p. 615,617
反应条件
potassium carbonate in N,N-dimethyl-formamide T=20°C;
参考文献
AstraZeneca AB; NPS PHARMACEUTICALS, INC.
Patent: US2007/259862 A1, 2007 ;
Location in patent: Page/Page column 29 ;
US 20070259862 A1
反应条件
1: thionyl chloride / 1.5 h / Heating 2: 0.5 h / Heating View Scheme
参考文献
Deady, Leslie W.
Australian Journal of Chemistry, 1985 , vol. 38, # 4 p. 637 - 641
反应条件
1: SOCl2 2: N2H4+H2O; ethanol View Scheme
参考文献
Fronk; Mosher
Journal of Organic Chemistry, 1959 , vol. 24, p. 196
