(S)-(+)-α-(三氟甲基)苄醇合成路线 （共 18 条）
反应条件
Birman's catalyst in chloroform T=28°C; 4 h; Inert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
Tetrahedron, , vol. 65, # 11 p. 2232 - 2238
反应条件
Birman's catalyst in chloroform T=28°C; 2 h; Inert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
Tetrahedron, , vol. 65, # 11 p. 2232 - 2238
反应条件
1.1: N-(3,5-ditrifluoromethylbenzyl)quinidinium bromide; [1,3-bis(2,6-di-iso-propylphenyl)imidazol-2-ylidene]copper (I) fluoride / toluene / 0.17 h / -78 °C / |Inert atmosphere 1.2: -78 °C / |Inert atmosphere 2.1: tetrabutyl ammonium fluoride / tetrahydrofuran / -20 °C / |Inert atmosphere View Scheme
参考文献
Organic and Biomolecular Chemistry, , vol. 10, # 47 p. 9334 - 9337
反应条件
tetraproline chiral stationary phase packed on HPLC column in hexane; isopropyl alcohol Resolution of racemate;
参考文献
Chirality, , vol. 24, # 4 p. 329 - 338
反应条件
sodium hydroxide Ambient temperature; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Bioscience, Biotechnology and Biochemistry, , vol. 59, # 2 p. 271 - 276
反应条件
sodium tetrahydroborate in solid 120 h; Ambient temperatureother reducing agent and conditions; Product distribution;
参考文献
Carbohydrate Research, , vol. 192, p. 363 - 365
反应条件
phosphate buffer; Pseudomonas lipase Amano AH; (2R-trans)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol T=30°C; pH=7.0; 240 h; Product distribution; Further Variations:Reagents;
参考文献
Tetrahedron Asymmetry, , vol. 13, # 4 p. 415 - 422
反应条件
glucose dehydrogenase; D-glucose; (R)-specific alcohol dehydrogenase from Candida maris IFO10003; Reduced nicotinamide-adenine dinucleotide in dimethyl sulfoxide T=50°C; pH=8.5; aq. phosphate bufferEnzymatic reaction;
参考文献
Kawano, Shigeru; Yano, Miho; Hasegawa, Junzo; Yasohara, Yoshihiko
Bioscience, Biotechnology and Biochemistry, 2011 , vol. 75, # 6 p. 1055 - 1060
