顺-11-十四碳烯-1-醇合成路线 （共 34 条）
反应条件
tetrafluoroboric acid; 2,4,6-trimethylphenyl iodide; 3-chloro-benzenecarboperoxoic acid in dichloromethane; water; acetonitrile T=50°C; 10 h; Inert atmosphere;
参考文献
Miyamoto, Kazunori; Ochiai, Masahito; Sei, Yoshihisa; Yamaguchi, Kentaro
Journal of the American Chemical Society, 2009 , vol. 131, # 4 p. 1382 - 1383
反应条件
pyridinium chlorochromate in dichloromethane 2 h; Ambient temperature;
参考文献
Mcelfresh, J. Steven; Millar, Jocelyn G.; Rubinoff, Daniel
Journal of Chemical Ecology, 2001 , vol. 27, # 4 p. 791 - 806
反应条件
quinoline; hydrogen; Pd-BaSO4 in hexane
T=20°C;
参考文献
Rossi, Renzo; Carpita, Adriano; Gaudenzi, Loretta; Quirici, Maria Grazia
Gazzetta Chimica Italiana, 1980 , vol. 110, # 4 p. 237 - 246
反应条件
toluene-4-sulfonic acid in methanol; water
T=50°C; 2 h;
参考文献
Michelot, Didier
Synthesis, 1983 , # 2 p. 130 - 134
反应条件
1: 51 percent / dimethylsulfoxide / 16 h / Ambient temperature
2: 1.) 2M BuLi / 1.) hexane, HMPT, 0 deg C, 30 min, 2.) 20 deg C, 12 h
3: p-TsOH / methanol / 2 h / Heating
4: 95 percent / H2, quinoline / Lindlar catalyst / pentane / 1 h / -10 °C
View Scheme
参考文献
Rossi, Renzo; Carpita, Adriano; Gaudenzi, Loretta; Quirici, Maria Grazia
Gazzetta Chimica Italiana, 1980 , vol. 110, # 4 p. 237 - 246
反应条件
1: 1.) 2M BuLi / 1.) hexane, HMPT, 0 deg C, 30 min, 2.) 20 deg C, 12 h
2: p-TsOH / methanol / 2 h / Heating
3: 95 percent / H2, quinoline / Lindlar catalyst / pentane / 1 h / -10 °C
View Scheme
参考文献
Rossi, Renzo; Carpita, Adriano; Gaudenzi, Loretta; Quirici, Maria Grazia
Gazzetta Chimica Italiana, 1980 , vol. 110, # 4 p. 237 - 246
反应条件
1: 90 percent / bromine / CCl4 / 0.5 h / 20 °C
2: 75 percent / 18-crown-6-ether, KOH / petroleum ether / 10 h / 90 - 110 °C
3: 1) n-BuLi / 1) benzene + THF, 20 deg C, 1 h; 2) HMPTA, 20 deg C, 6 h.
4: 95 percent / hydrogen, quinoline / 5percent Pd/BaSO4 / hexane / 20 °C
View Scheme
参考文献
Zakharkin, L. I.; Guseva, V. V.
Chemistry of Natural Compounds, 1984 , vol. 20, # 6 p. 733 - 736
Khimiya Prirodnykh Soedinenii, 1984 , vol. 20, # 6 p. 776 - 779
反应条件
1: 71 percent / stearic acid, palmitic acid / 350 °C / 260 Torr
2: 90 percent / bromine / CCl4 / 0.5 h / 20 °C
3: 75 percent / 18-crown-6-ether, KOH / petroleum ether / 10 h / 90 - 110 °C
4: 1) n-BuLi / 1) benzene + THF, 20 deg C, 1 h; 2) HMPTA, 20 deg C, 6 h.
5: 95 percent / hydrogen, quinoline / 5percent Pd/BaSO4 / hexane / 20 °C
View Scheme
参考文献
Zakharkin, L. I.; Guseva, V. V.
Chemistry of Natural Compounds, 1984 , vol. 20, # 6 p. 733 - 736
Khimiya Prirodnykh Soedinenii, 1984 , vol. 20, # 6 p. 776 - 779
反应条件
1: 65 percent / ethyl acetate / 450 - 470 °C / quartz tube packed with glass
2: 98 percent / KOH / methanol; H2O / 8 h / Heating
3: 90 percent / bromine / CCl4 / 0.5 h / 20 °C
4: 75 percent / 18-crown-6-ether, KOH / petroleum ether / 10 h / 90 - 110 °C
5: 1) n-BuLi / 1) benzene + THF, 20 deg C, 1 h; 2) HMPTA, 20 deg C, 6 h.
6: 95 percent / hydrogen, quinoline / 5percent Pd/BaSO4 / hexane / 20 °C
View Scheme
参考文献
Zakharkin, L. I.; Guseva, V. V.
Chemistry of Natural Compounds, 1984 , vol. 20, # 6 p. 733 - 736
Khimiya Prirodnykh Soedinenii, 1984 , vol. 20, # 6 p. 776 - 779
反应条件
1: 98 percent / KOH / methanol; H2O / 8 h / Heating
2: 90 percent / bromine / CCl4 / 0.5 h / 20 °C
3: 75 percent / 18-crown-6-ether, KOH / petroleum ether / 10 h / 90 - 110 °C
4: 1) n-BuLi / 1) benzene + THF, 20 deg C, 1 h; 2) HMPTA, 20 deg C, 6 h.
5: 95 percent / hydrogen, quinoline / 5percent Pd/BaSO4 / hexane / 20 °C
View Scheme
参考文献
Zakharkin, L. I.; Guseva, V. V.
Chemistry of Natural Compounds, 1984 , vol. 20, # 6 p. 733 - 736
Khimiya Prirodnykh Soedinenii, 1984 , vol. 20, # 6 p. 776 - 779
