(Z)-11-十六碳烯-1-乙酸盐合成路线 （共 74 条）
反应条件
1: 79 percent / pyridine / 1.) -5 deg C, 6 h; 2.) 0 deg C, 12 h 2: 53 percent / sodium iodide, zinc dust / tetrahydrofuran / 1.) 65-70 deg C, 3 h; 2.) 20 deg C, 3 h 3: 1.) 2percent O3 in O2; 2.) sodium tetrahydroborate / 1.) cyclohexane, methanol; 2.) room temp., 15 h 4: 1.) isobutylmagnesium bromide; 2.) C5H5TiCl2 / 1.) diethyl ether, 0 deg C, 15 min; 2.) room temp., 1-1,5 h 5: 90 percent / pyridine View Scheme
参考文献
Chemistry of Natural Compounds, , vol. 23, # 3 p. 365 - 368
Khimiya Prirodnykh Soedinenii, , # 3 p. 440 - 444
反应条件
1: 53 percent / sodium iodide, zinc dust / tetrahydrofuran / 1.) 65-70 deg C, 3 h; 2.) 20 deg C, 3 h 2: 1.) 2percent O3 in O2; 2.) sodium tetrahydroborate / 1.) cyclohexane, methanol; 2.) room temp., 15 h 3: 1.) isobutylmagnesium bromide; 2.) C5H5TiCl2 / 1.) diethyl ether, 0 deg C, 15 min; 2.) room temp., 1-1,5 h 4: 90 percent / pyridine View Scheme
参考文献
Chemistry of Natural Compounds, , vol. 23, # 3 p. 365 - 368
Khimiya Prirodnykh Soedinenii, , # 3 p. 440 - 444
反应条件
1: 1.) B2H6, 2.) H2O2/3N NaOH / 1.) diglyme, 5h, 2.) room temperature, overnight 2: 85 percent / PBr3 / benzene / 5 h / Ambient temperature 3: 22 g / acetonitrile / 8 h / Heating 4: 1.) potassium tert-butanolate / 1.) DMF, 20 deg C, 3h, 2.) 5h 5: LiAlH4 / diethyl ether / 3 h / Heating 6: pyridine / 10 h / Ambient temperature View Scheme
参考文献
Chemistry of Natural Compounds, , vol. 16, # 1 p. 82 - 85
Khimiya Prirodnykh Soedinenii, , vol. 16, # 1 p. 97 - 102
反应条件
1: 22 g / acetonitrile / 8 h / Heating 2: 1.) potassium tert-butanolate / 1.) DMF, 20 deg C, 3h, 2.) 5h 3: LiAlH4 / diethyl ether / 3 h / Heating 4: pyridine / 10 h / Ambient temperature View Scheme
参考文献
Chemistry of Natural Compounds, , vol. 16, # 1 p. 82 - 85
Khimiya Prirodnykh Soedinenii, , vol. 16, # 1 p. 97 - 102
反应条件
1: 85 percent / PBr3 / benzene / 5 h / Ambient temperature 2: 22 g / acetonitrile / 8 h / Heating 3: 1.) potassium tert-butanolate / 1.) DMF, 20 deg C, 3h, 2.) 5h 4: LiAlH4 / diethyl ether / 3 h / Heating 5: pyridine / 10 h / Ambient temperature View Scheme
参考文献
Chemistry of Natural Compounds, , vol. 16, # 1 p. 82 - 85
Khimiya Prirodnykh Soedinenii, , vol. 16, # 1 p. 97 - 102
反应条件
1: LiAlH4 / diethyl ether / 3 h / Heating 2: pyridine / 10 h / Ambient temperature View Scheme
参考文献
Chemistry of Natural Compounds, , vol. 16, # 1 p. 82 - 85
Khimiya Prirodnykh Soedinenii, , vol. 16, # 1 p. 97 - 102
反应条件
1: 1.) B2H6, 2.) H2O2/3N NaOH / 1.) diglyme, 5h, 2.) room temperature, overnight 2: H2/RaNi / ethyl acetate / 4 h / 80 °C / 76000.1 Torr 3: 85 percent / PBr3 / benzene / 5 h / Ambient temperature 4: 22 g / acetonitrile / 8 h / Heating 5: 1.) potassium tert-butanolate / 1.) DMF, 20 deg C, 3h, 2.) 5h 6: LiAlH4 / diethyl ether / 3 h / Heating 7: pyridine / 10 h / Ambient temperature View Scheme
参考文献
Chemistry of Natural Compounds, , vol. 16, # 1 p. 82 - 85
Khimiya Prirodnykh Soedinenii, , vol. 16, # 1 p. 97 - 102
反应条件
1: 1.) potassium tert-butanolate / 1.) DMF, 20 deg C, 3h, 2.) 5h 2: LiAlH4 / diethyl ether / 3 h / Heating 3: pyridine / 10 h / Ambient temperature View Scheme
参考文献
Chemistry of Natural Compounds, , vol. 16, # 1 p. 82 - 85
Khimiya Prirodnykh Soedinenii, , vol. 16, # 1 p. 97 - 102
反应条件
1: H2/RaNi / ethyl acetate / 4 h / 80 °C / 76000.1 Torr 2: 85 percent / PBr3 / benzene / 5 h / Ambient temperature 3: 22 g / acetonitrile / 8 h / Heating 4: 1.) potassium tert-butanolate / 1.) DMF, 20 deg C, 3h, 2.) 5h 5: LiAlH4 / diethyl ether / 3 h / Heating 6: pyridine / 10 h / Ambient temperature View Scheme
参考文献
Chemistry of Natural Compounds, , vol. 16, # 1 p. 82 - 85
Khimiya Prirodnykh Soedinenii, , vol. 16, # 1 p. 97 - 102
反应条件
1: 50 percent / Li2CuCl4 / tetrahydrofuran / 4 h / -10 °C 2: 68 percent / acetic acid / 35 - 40 °C View Scheme
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 26, # 1-12 p. 1069 - 1070
