1-甲基-4-(4-硝基苯氧基)苯合成路线 （共 26 条）
反应条件
1: 4-nitro-phenol With sodium hydride in toluene T=100°C; 0.5 h; 2: 4-methyl-chlorobenzene With 1-(2-methoxyethyl)-3-(2,3,5,6-tetramethylbenzyl)imidazolinium bromide; palladium diacetate T=100°C; 2 h;
参考文献
Akkoc, Mitat; Guerbuez, Nevin; Cetinkaya, Engin; Oezdemir, Ismail
Synlett, 2008 , # 12 p. 1781 - 1784
反应条件
potassium hydroxide in N,N-dimethyl-formamide 1 h; Heating;
参考文献
Ohta, Akihiro; Iwasaki, Yoko; Akita, Yasuo
Synthesis, 1982 , # 10 p. 828 - 829
反应条件
potassium carbonate in acetonitrile T=50°C; 24 h; regioselective reaction;
参考文献
Kakinuma, Yohji; Moriyama, Katsuhiko; Togo, Hideo
Synthesis (Germany), 2013 , vol. 45, # 2 art. no. SS-2012-F0786-OP, p. 183 - 188
反应条件
potassium hydroxide in dimethyl sulfoxide T=20°C; 16 h;
参考文献
Dey, Archan; Desiraju, Gautam R.
Chemical Communications, 2005 , # 19 p. 2486 - 2488
反应条件
p-cresol T=150 - 160°C;
参考文献
Rarick; Brewster; Dains
Journal of the American Chemical Society, 1933 , vol. 55, p. 1289
反应条件
in N,N-dimethyl-formamide T=100°C; 24 h;
参考文献
Huang; Zhu; Xu
Synthetic Communications, 2001 , vol. 31, # 18 p. 2823 - 2828
反应条件
in tert-butyl alcohol; benzene
参考文献
Burroughs Wellcome Co.
Patent: US4329365 A1, 1982 ;
反应条件
copper(I) oxide in N,N-dimethyl acetamide T=166°C;
参考文献
Bacon,R.G.R.; Stewart,O.J.
Journal of the Chemical Society, 1965 , p. 4953 - 4961
反应条件
potassium carbonate in acetonitrile T=50°C; 24 h; Overall yield = 75 percent; regioselective reaction;
参考文献
Kakinuma, Yohji; Moriyama, Katsuhiko; Togo, Hideo
Synthesis (Germany), 2013 , vol. 45, # 2 art. no. SS-2012-F0786-OP, p. 183 - 188
反应条件
p-cresol; naphthalene T=230°C;
参考文献
Cook
Journal of the American Chemical Society, 1903 , vol. 25, p. 61
